Protein Info for BWI76_RS01870 in Klebsiella michiganensis M5al

Annotation: diacylglycerol kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01219: DAGK_prokar
  • amino acids 16 to 116 (101 residues), 120.9 bits, E=9.3e-40

Best Hits

Swiss-Prot: 83% identical to KDGL_ECOL6: Diacylglycerol kinase (dgkA) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K00901, diacylglycerol kinase [EC: 2.7.1.107] (inferred from 90% identity to kpn:KPN_04430)

MetaCyc: 83% identical to diacylglycerol kinase (Escherichia coli K-12 substr. MG1655)
Diacylglycerol kinase. [EC: 2.7.1.107]

Predicted SEED Role

"Diacylglycerol kinase (EC 2.7.1.107)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 2.7.1.107)

MetaCyc Pathways

• phosphatidate metabolism, as a signaling molecule (2/5 steps found)
• diacylglycerol and triacylglycerol biosynthesis (3/7 steps found)
• type I lipoteichoic acid biosynthesis (S. aureus) (5/17 steps found)

KEGG Metabolic Maps

• Glycerolipid metabolism
• Glycerophospholipid metabolism
• Phosphatidylinositol signaling system

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.107

Sequence Analysis Tools

See A0A285AWC6 at UniProt or InterPro

Protein Sequence (122 amino acids)

>BWI76_RS01870 diacylglycerol kinase (Klebsiella michiganensis M5al)
MANNTTGLTRIIKAAGYSWKGFRAAWVNEAAFRQEGIAAIIAVAIACWLDVDAITRVLLI
SSVLLVMIVEIINSAIEAVVDRIGPEHHELSGRAKDMGSAAVLLAIIIALIAWGTLLWAN
YR