Protein Info for BWI76_RS01080 in Klebsiella michiganensis M5al

Annotation: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 364 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 45 to 66 (22 residues), see Phobius details amino acids 72 to 89 (18 residues), see Phobius details amino acids 101 to 126 (26 residues), see Phobius details amino acids 132 to 151 (20 residues), see Phobius details amino acids 161 to 179 (19 residues), see Phobius details amino acids 185 to 204 (20 residues), see Phobius details amino acids 213 to 232 (20 residues), see Phobius details amino acids 244 to 263 (20 residues), see Phobius details amino acids 294 to 315 (22 residues), see Phobius details amino acids 321 to 339 (19 residues), see Phobius details TIGR02380: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase" amino acids 8 to 350 (343 residues), 547.1 bits, see alignment E=8.7e-169 PF00953: Glycos_transf_4" amino acids 76 to 233 (158 residues), 113 bits, see alignment E=7.2e-37

Best Hits

Swiss-Prot: 85% identical to WECA_ECOLI: Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase (wecA) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 96% identity to eae:EAE_07795)

MetaCyc: 85% identical to UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase (Escherichia coli O157)
GLCNACPTRANS-RXN [EC: 2.7.8.33]

Predicted SEED Role

"Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-)" in subsystem Methicillin resistance in Staphylococci or Teichoic and lipoteichoic acids biosynthesis (EC 2.7.8.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.8.-

Use Curated BLAST to search for 2.7.8.- or 2.7.8.33

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AVV2 at UniProt or InterPro

Protein Sequence (364 amino acids)

>BWI76_RS01080 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase (Klebsiella michiganensis M5al)
MNLLTAITELISIFLFTTLFIFIARKAAKRVGLVDKPNYRKRHQGLIPLVGGISVFAGIC
FTFAIADYYIPHARLYLGCAGVLVLVGALDDRFDISVKIRAVIQAAIAVIMMMVGNLHLS
SLGFIFGSWELVLGPFGFFLTLFAVWAAINAFNMVDGIDGLLGGLSSVSFAATGIILWFD
GQYSLAMWCFAMIAAILPYILLNLGALGRRYKVFMGDAGSTMIGFTIIWILLETTQGKTH
PISPVTALWIIAIPLMDMVAIMYRRLRKGMSPFSPDRQHIHHLIMRAGFTSRQAFVLITL
AAALLALVGVVAEYTRIVPEWVMLILFLVAFFLYGYCIKRAWKVARMVKRIRRRIRRHSG
NNPN