Protein Info for BWI76_RS00520 in Klebsiella michiganensis M5al

Annotation: transcription regulator of PTS system

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 867 PF00158: Sigma54_activat" amino acids 90 to 259 (170 residues), 135.3 bits, see alignment E=5.1e-43 PF07728: AAA_5" amino acids 116 to 255 (140 residues), 24 bits, see alignment E=1e-08 PF00004: AAA" amino acids 116 to 258 (143 residues), 29.6 bits, see alignment E=2.6e-10 PF03610: EIIA-man" amino acids 513 to 624 (112 residues), 31.7 bits, see alignment E=4.5e-11 PF00874: PRD" amino acids 773 to 855 (83 residues), 30.6 bits, see alignment E=1.1e-10

Best Hits

KEGG orthology group: None (inferred from 85% identity to cro:ROD_38561)

Predicted SEED Role

"NtrC family Transcriptional regulator, ATPase domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AVL0 at UniProt or InterPro

Protein Sequence (867 amino acids)

>BWI76_RS00520 transcription regulator of PTS system (Klebsiella michiganensis M5al)
MALSAKEKLFQKIVTHYAHKPAGFTAQDCADFMQVNRSVISHYLNRLCDDGHLSKENTRP
VRFFVQTNGKESVQASLIVSKKHDAFQPLIGAHGSLAEAVALCRSAVDYPGDGLPILLSG
ESGVGKSHLATLIYQYALERGVIAADKPFVELNCADYANNPELLSATLFGYIRGAFTGAD
REKRGAFDDADGGFLFLDEVHRLSAENQEKLFLFMDKGYFYRLGDNRTRHPASLRFIFAT
TENIDTVLLNTFRRRIPVRVTLPNYISRPLTERVAQVSHFLHQEAHSLRRDIHLDNQLMH
QLVASPVRGNIGELKNQIKVMCASAWSDNREAEVITLRGPASGGEIIRIAANADNDALCA
SQFLPKAMRDEVIFRDFCHSGNVLLLNRKMEQLLTTVSGAVAAEALYSGYIWQNTVHALD
ELESLTGIFCSQEIRKAVWLCVSYALHDAEETVNAGELQTISDYVSAKARLLAEECLALL
SKHVTRQPLPLLLPLLSCAFHTLAGEDDPIQGIIVSHGRATASSIAGIANQLTGGYYFKA
FDMANATSTREIIDLLIAHVSRLKQGAGLIILVDMGSLKEIYEEIKLHLHGELLVINNVS
TAMALDIAAKIQDKLSMEAIIESAKGAYEVETRYYAGVLPGNKIIISCISGEGISRKLKD
IVQRFLAQEEIDIITMEYDDLKWKIAHADPALNGTRLIITTTDLEAGYIPLLSVEQLIKE
KTLVLKRDYFNGLLMEGGLEPMIDEVVKLFTVEGVASRLNFLNPVVIIDEVEAVIKQYES
FYKIHFESYLRINLFMHIALMIERVMVNNGVRHREETALTLEQQAFVAVHDTFFQALNRK
YNITLPLTEVLMIYEIMEPWIAFAPEH