Protein Info for BWI76_RS00425 in Klebsiella michiganensis M5al

Annotation: D-tyrosyl-tRNA(Tyr) deacylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase
  • amino acids 1 to 145 (145 residues), 247.9 bits, E=2.1e-78
• PF02580: Tyr_Deacylase
  • amino acids 3 to 144 (142 residues), 194 bits, E=8.1e-62

Best Hits

Swiss-Prot: 94% identical to DTD_ENT38: D-aminoacyl-tRNA deacylase (dtd) from Enterobacter sp. (strain 638)

KEGG orthology group: K07560, D-tyrosyl-tRNA(Tyr) deacylase [EC: 3.1.-.-] (inferred from 94% identity to eco:b3887)

MetaCyc: 94% identical to D-aminoacyl-tRNA deacylase (Escherichia coli K-12 substr. MG1655)
RXN-15041 [EC: 3.1.1.96]; 3.1.1.96 [EC: 3.1.1.96]; 3.1.1.96 [EC: 3.1.1.96]; 3.1.1.96 [EC: 3.1.1.96]; 3.1.1.96 [EC: 3.1.1.96]

Predicted SEED Role

"D-tyrosyl-tRNA(Tyr) deacylase (EC 3.6.1.n1)" (EC 3.6.1.n1)

Isozymes

Compare fitness of predicted isozymes for: 3.1.-.-

Use Curated BLAST to search for 3.1.-.- or 3.1.1.96 or 3.6.1.n1

Sequence Analysis Tools

See A0A285AVK9 at UniProt or InterPro

Protein Sequence (145 amino acids)

>BWI76_RS00425 D-tyrosyl-tRNA(Tyr) deacylase (Klebsiella michiganensis M5al)
MIALIQRVSRASVTVEGEVTGEIGPGLLVLLGVERDDDEQKANRLCERVLGYRIFSDAEG
KMNLNVQQAGGSVLVVSQFTLAADTERGMRPGFSKGAAPDKAEALYAYFVERCREQKMNT
QTGRFAADMQVSLVNDGPVTFWLQV