Protein Info for BPHYT_RS31135 in Burkholderia phytofirmans PsJN

Annotation: hexuranate MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 429 transmembrane" amino acids 18 to 35 (18 residues), see Phobius details amino acids 56 to 76 (21 residues), see Phobius details amino acids 87 to 108 (22 residues), see Phobius details amino acids 118 to 137 (20 residues), see Phobius details amino acids 149 to 172 (24 residues), see Phobius details amino acids 178 to 196 (19 residues), see Phobius details amino acids 237 to 257 (21 residues), see Phobius details amino acids 273 to 294 (22 residues), see Phobius details amino acids 306 to 326 (21 residues), see Phobius details amino acids 331 to 353 (23 residues), see Phobius details amino acids 365 to 385 (21 residues), see Phobius details amino acids 397 to 419 (23 residues), see Phobius details PF07690: MFS_1" amino acids 26 to 382 (357 residues), 189.3 bits, see alignment E=4.6e-60

Best Hits

KEGG orthology group: K08191, MFS transporter, ACS family, hexuronate transporter (inferred from 100% identity to bpy:Bphyt_6282)

Predicted SEED Role

"Hexuronate transporter" in subsystem Alginate metabolism or D-Galacturonate and D-Glucuronate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TB13 at UniProt or InterPro

Protein Sequence (429 amino acids)

>BPHYT_RS31135 hexuranate MFS transporter (Burkholderia phytofirmans PsJN)
MKILEAGSVADQTAVGRYRWTICALIFFATTINYMDRQMLGLLAPLLQKDIGWTQVQYAQ
TVMVFTVAYAVGLATFGRIADRISTKVVYGGAMAMWSLAAMLHAIAATVPGFAAVRGLLG
FGEAANFPVAIRTTALWFPKKERALATGLWNMGATVGGIVAPAFVPIAAVMWGWRATFIA
GGAAGFVWLAVWLLVYRPPAEHASVSKRELDYINSDRDESVEQRVSWLSVLKYRETWAFI
FGKLLTDPVWWFYLFWLPKWLNESRHIDIANLGLPLIVIYTMASVGSVAGGWLSSRLMQR
SHKPNVARKIAMGVCALCVLPIATLSLFQSLWYAVFAVGLAAAAHQGWSANLVTTVGDVF
PRRMVGTVVGIGGVAGMIGSFFYSGVIGETLQRTGQYWVLFAVGASAYLVALGIIHLLMP
RMTPVKLEH