Protein Info for BPHYT_RS29850 in Burkholderia phytofirmans PsJN

Annotation: protein tyrosine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 736 transmembrane" amino acids 32 to 52 (21 residues), see Phobius details amino acids 448 to 468 (21 residues), see Phobius details TIGR01005: exopolysaccharide transport protein family" amino acids 15 to 731 (717 residues), 413.9 bits, see alignment E=1.3e-127 PF02706: Wzz" amino acids 17 to 109 (93 residues), 55.2 bits, see alignment E=1.8e-18 PF13807: GNVR" amino acids 391 to 470 (80 residues), 102.2 bits, see alignment E=3e-33 TIGR01007: capsular exopolysaccharide family" amino acids 530 to 731 (202 residues), 126.4 bits, see alignment E=1.1e-40 PF01656: CbiA" amino acids 550 to 586 (37 residues), 27.4 bits, see alignment 7e-10 PF13614: AAA_31" amino acids 558 to 668 (111 residues), 32.5 bits, see alignment E=2.1e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_6020)

Predicted SEED Role

"Tyrosine-protein kinase Wzc (EC 2.7.10.2)" in subsystem Colanic acid biosynthesis (EC 2.7.10.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.10.2

Use Curated BLAST to search for 2.7.10.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T884 at UniProt or InterPro

Protein Sequence (736 amino acids)

>BPHYT_RS29850 protein tyrosine kinase (Burkholderia phytofirmans PsJN)
MKLLDRERSADALGEKEITLSEVIALLSENRLLIALTTAAMLFLGIAYAFFGTPLYKADV
TIQVDSNSGSDTLNDKLGELASLFQSKASTDAEIELIRSRMVVEETVRSLQLDVNATPHR
FPLIGALIARQALPGSPASAFLGLSSFAWGGETLGVAQFDVPAALYDQPFKLMVGAGQAF
ELRDADGHTVLRGHVGIAEQGVTRFGSVQLRVDHMIARVGTSFNLKRSSTQLTTADLQSA
LNINEKAKQSGIVAVSLEGEDAARTAATVNRVASIYVQRNVDRKSAQAQQMLQFLADQLP
QLRADLDDAEARYNAFRTQNGTVDLETEGKLLLQSIVDSKTKLIELQQQRSALAQRYTVE
HPSIQAIDAQIDELQEQQRSFGAKVAALPNIQQQALRLMRDVRVDTDLYTKLLDSTQQLR
VLKAGQLGNVHTIDYAEVAEKAVKPKKALVIALSGLIGVVLGCAIAFVRSTLNRGLETPS
EIEGAVGVPVYAIVSRSARQRTLQQSARGGGSGLNVLAVAQPDDVAVEGIRSLRTALQFG
LLKSHNNIVMLTGPRPDVGKSFLSVNLATVLSAGGKRVLLVDSDMRRGDVHRYFSLPSKP
GLSDVIGGVEPSSAVHYQVLPHLDVLMSGSVASSPAEILMSDSFGSLLAQFSKEYDVVIV
DSPPVLAVTDPVLIGKHAGLTLLVIRHGRHSAAELQESVRQLSSAGHAVDGVLLNAVPQR
ASAYGAFSEYGAEKSA