Protein Info for BPHYT_RS28960 in Burkholderia phytofirmans PsJN

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 887 PF08448: PAS_4" amino acids 64 to 159 (96 residues), 24.7 bits, see alignment E=6e-09 TIGR00229: PAS domain S-box protein" amino acids 191 to 303 (113 residues), 40.1 bits, see alignment E=1.8e-14 PF08447: PAS_3" amino acids 202 to 289 (88 residues), 57.3 bits, see alignment E=4e-19 PF02518: HATPase_c" amino acids 444 to 563 (120 residues), 71 bits, see alignment E=2.8e-23 PF00072: Response_reg" amino acids 587 to 698 (112 residues), 51.6 bits, see alignment E=2.4e-17 amino acids 769 to 874 (106 residues), 53.6 bits, see alignment E=6e-18

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_5841)

Predicted SEED Role

"Two-component hybrid sensor and regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TFS1 at UniProt or InterPro

Protein Sequence (887 amino acids)

>BPHYT_RS28960 histidine kinase (Burkholderia phytofirmans PsJN)
MPFPAHDHGCSGWRGEMAQRISAFDWAATGLGAIENWPRSLTATVQLLLASPVPLVLLWG
KPGYMIYNDAYAVFAGGRHPYLLGCPVEHGWPEVADFNRHVMATCLAGGTLSYRDKELVL
LRDGKPEDVWMDLYYSPVADDSGAPAGVLAVVVETTTRVLTERWRQRAEAELHETNERLQ
LALNTGTVLGTWVLDVRTGKVSGDERFARTFSFRQEEAAKGVERHAAVHMIHPDDQALND
QLTAEAIRTRQPFRAEFRIRRPDGDYIWVQANGQCEFDEHGEPTRFPGVLIDIHERKIAE
QSLRQLTETLEQRVADALAARALAEEQLRQAQKMEAIGSLTGGVAHDFNNVLQVINGNLQ
MLAADAGGHPATLRRLSAATDAVKRGAKLAAHLLAFARRQPLSPTVLNPRRLLSGMSEML
HRALGETVRIDTVLNDDLWNVQADRNQLENALLNLAINARDAMQGDGTLTVRAANRVLDT
TFCQDKPELSPGEYVVFSVADSGAGMPPEILQRVFEPFFTTKPDGHGTGLGLSMVFGFLR
QSGGHTLIESEVGRGTTVSLFFPRCCEAETSEAVDDTEAPSGGGETILVVEDDADVRLTA
VEMLAQLGYKVLTASSGDAAIEFIESDVPIDLLFTDVVMPGKIKSVELAQRAATRSPAVP
TLFTSGYARDEIVHHGKLDAGITLLSKPYRRDDLARKVRGVLRAGAAAAAGMALPASVAE
GQIAACVPPAAYDRVGESSQESRPPEVEAIPQTKSSLARARSPGTPARVLLVEDDMNSRE
AFNDLLNALGLDCTAVGSAEEALPLVPAQHFDILFTDLTLPGMSGDCLARAMLRQQPGIR
VLLVSGYGKSAQIGDAIPGARLLGKPLDIAELRRELAGWIDHTEEAS