Protein Info for BPHYT_RS27130 in Burkholderia phytofirmans PsJN

Annotation: heat-labile enterotoxin A chain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 965 PF01375: Enterotoxin_a" amino acids 457 to 673 (217 residues), 241.4 bits, see alignment E=6.7e-76

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_5460)

Predicted SEED Role

"Heat-labile enterotoxin IIB, A chain precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TE17 at UniProt or InterPro

Protein Sequence (965 amino acids)

>BPHYT_RS27130 heat-labile enterotoxin A chain (Burkholderia phytofirmans PsJN)
MTTSAIGNGPKNFDDADSSARQGDSSGTQQQAAAEQDARASRRLSGQQPPSLTPSGQRMD
QRAHGPSFRISQGSAQTRQDEWDDPARIQGMTSATLNARAPTDQPGPKSSFASTYSRLSL
SAATTQRPGIDATADTATGHMVASGTPATGRDKRQTPPTSGPYEQTYHAYMDSAAGENGV
SERMLSSAAGQPDVLTDHCAGLVWLTMHEVMAARSHDLRGATDSVYQQLLHPSTRRSLLD
EIGRLQMANEEAPPSDVPGYEMRPGGVRMTSAGAVVSDLQRHFSTPLPSRDGLGTAQDTF
VDMTLRFPHGDDHAILIQRANRSADYRTDEYQLYDPNYGVFTYRGFDALAAGIKRLYEHG
YRQFGGVTGASTTYYADPLTWRPYTGVAPDAHRAMMQNTALRAFGAERTPVLAPTDPGQL
PPPPAFDQPGPSGWDGGSHTEFKRSTDAHGPDHPFALFRPSQTSPDQLKKQQGFSVEDTA
LGNTNLDLHDSIVTGNRAATDGGGYVGTFTGRGTAQERIDATPEKKGYIYYVAPSPNMVD
VPGSLGRKHARAPGDGEVAAMGRIDYTQVRGWQKYENGKLGPYIANPDYRWDVYDGTRTA
GARPQLAHFSPDDPAWADADHRPFVTPFQQNGKTLYRPNEDPALVQARFYQHANADVSQR
VDDQTHHLEYRGPVTIGPEWGNGGSDNRSRLNFTAGYPSIDRSSANRGGDRFRMGDDGRI
HLANDDSKVLRIDGDGNAYIGSDPGAGSLNGVFFHAPNGALIHAEDGKLLTEGAMAYTPY
VAASHGQSGLIDRQRWTFRDSSGNTVQPPLPLVAFRNSTAGSPDQLRRFYDDPDSALPDG
TSHFVTSVPGVKSHEGYKFVSYPDHIAPGDAAVARNWLAAHNAAWLFKDGFYAVASGPDT
LEVRTLGGTPVWRAQIDPVTGHETYFMLQNGISSNYEAPPRTWQRVLDNEKRDAALSQRM
GQNYM