Protein Info for BPHYT_RS26965 in Burkholderia phytofirmans PsJN
Updated annotation (from data): L-lactate dehydrogenase, LldG subunit
Rationale: Specifically important for utilization of L-lactate and D,L-lactate as well as L-rhamnose and L-fucose, which are catabolized via L-lactate. This gene has additional phenotypes which were not found for the other subunits and are not explained.
Original annotation: hypothetical protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00782, hypothetical protein (inferred from 100% identity to bpy:Bphyt_5427)Predicted SEED Role
"Predicted L-lactate dehydrogenase, hypothetical protein subunit SO1518" in subsystem Lactate utilization
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See B2TBY7 at UniProt or InterPro
Protein Sequence (195 amino acids)
>BPHYT_RS26965 L-lactate dehydrogenase, LldG subunit (Burkholderia phytofirmans PsJN) MATREAFLDKVRQAQPPSRPRPEVPLFDAPGGDLRVRFTAALQAMGGTCVQAVSATDVSG LIRERFGAEASVASATTEVPGTRALTADTEPASLQDIDVGVVRARFGVAETGSVWFSERE YVVNALGYIVQHLIVLLDPAQLIDGLQDVYRRDDFRDARYAALVTGPSATADIEGVLIRG AQGVRSLTVVWLAAQ