Protein Info for BPHYT_RS26405 in Burkholderia phytofirmans PsJN

Annotation: glycogen synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 529 signal peptide" amino acids 1 to 13 (13 residues), see Phobius details TIGR02095: glycogen/starch synthase, ADP-glucose type" amino acids 4 to 485 (482 residues), 526.2 bits, see alignment E=3.7e-162 PF08323: Glyco_transf_5" amino acids 4 to 242 (239 residues), 229.9 bits, see alignment E=9.3e-72 PF13439: Glyco_transf_4" amino acids 19 to 230 (212 residues), 35.6 bits, see alignment E=2.4e-12 PF13579: Glyco_trans_4_4" amino acids 19 to 229 (211 residues), 39.8 bits, see alignment E=1.5e-13 PF13692: Glyco_trans_1_4" amino acids 302 to 449 (148 residues), 42.1 bits, see alignment E=2.6e-14 PF00534: Glycos_transf_1" amino acids 302 to 449 (148 residues), 49.3 bits, see alignment E=1.1e-16

Best Hits

Swiss-Prot: 53% identical to GLGA_BURTA: Glycogen synthase (glgA) from Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)

KEGG orthology group: K00703, starch synthase [EC: 2.4.1.21] (inferred from 100% identity to bpy:Bphyt_5314)

Predicted SEED Role

"Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21)" in subsystem Glycogen metabolism (EC 2.4.1.21)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.21

Use Curated BLAST to search for 2.4.1.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TBM1 at UniProt or InterPro

Protein Sequence (529 amino acids)

>BPHYT_RS26405 glycogen synthase (Burkholderia phytofirmans PsJN)
MPLNVLLVASEALPLAKSGGLGDMVSAYAAALRDAGVDVSILMPAYPAALERAVDVEPVA
RMTGLPGGDARLLRGQMPDTGVPVLLLQMDHLFAREGLYRDPQGRDYLDNLTRFASLAAA
AARVARGVRNVKRPDIVHAHDWHAGLTPLYLRLAGVAAKSVFTIHNLAFQGNHPLAMGGW
IGVPPELLAPALSDERSIEFYGSLSMMKAGIVHSDRVTTVSRRYAREILTPHFGHGMEGV
LQAQAAKLSGIVNGIDTSVWNPATDKHIARPYSVDDTAGKQACKRELQQAFGLTRDPFAP
LVAIGSRLTEQKLADVVVHTLPALLERHPRLQFAILGQGEPGLEQALQDVAAAWPGRVGV
QIGYDERRAHMLHAGADILLHGSRFEPCGLTQLYAMRYGTIPVASRVGGLADTIVDYVPH
DPRGEQKATGFLFDGESPDDVMHALGRALAAFVQPSSWHVLQRNAMSRDFGWDASTANYL
ALYADLVDARPALRDPRVRKTPLRARTAIAASSKREEFNTGIGEMARSA