Protein Info for BPHYT_RS25795 in Burkholderia phytofirmans PsJN

Annotation: LacI family transcription regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 334 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF13407: Peripla_BP_4" amino acids 31 to 288 (258 residues), 209.5 bits, see alignment E=6.6e-66 PF00532: Peripla_BP_1" amino acids 69 to 241 (173 residues), 25.4 bits, see alignment E=9.3e-10

Best Hits

KEGG orthology group: K02058, simple sugar transport system substrate-binding protein (inferred from 100% identity to bpy:Bphyt_5192)

Predicted SEED Role

"ABC transporter, periplasmic sugar-binding protein precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TCX7 at UniProt or InterPro

Protein Sequence (334 amino acids)

>BPHYT_RS25795 LacI family transcription regulator (Burkholderia phytofirmans PsJN)
MKLTRLGAALAAGALTVGVIAAAQAATNETIVTVVKVTGINWFNRMDDGVKQFAKDNPNI
NAYQTGPGRADAAQQLKIIEDLIAKKVTAIAVVPYDPPTLEPALKKAMDRGIKVVTHEAD
NAKNTMVDIEAFDNTAYGAGLNERLASCMHDDGKWAVLVGSLGSRSQVQWADGGIGNAKA
KYPKMNLVEPKLETNNDGERAYEVAKEVLRKHPDLKGFQGSSSLDVIGIGRAVEEAGMQG
KICVYGTGLPTEAGKFLESGAINGIAFWDPKLAGIAMNKVAQMLVDGKTVENGADLGIPG
YTKVTVAKGPGKGIIVRGQGWVNVDKSNYKQYPF