Protein Info for BPHYT_RS25545 in Burkholderia phytofirmans PsJN

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 647 transmembrane" amino acids 251 to 275 (25 residues), see Phobius details amino acids 296 to 320 (25 residues), see Phobius details amino acids 335 to 355 (21 residues), see Phobius details amino acids 379 to 407 (29 residues), see Phobius details amino acids 413 to 434 (22 residues), see Phobius details amino acids 454 to 471 (18 residues), see Phobius details amino acids 477 to 495 (19 residues), see Phobius details amino acids 507 to 527 (21 residues), see Phobius details PF11412: DsbD_N" amino acids 13 to 120 (108 residues), 65.1 bits, see alignment E=9.3e-22 PF02683: DsbD" amino acids 258 to 466 (209 residues), 34.3 bits, see alignment E=3.4e-12 PF13899: Thioredoxin_7" amino acids 539 to 626 (88 residues), 45.9 bits, see alignment E=8e-16

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_5139)

Predicted SEED Role

"Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase (EC 1.8.1.8)" in subsystem Biogenesis of c-type cytochromes or Periplasmic disulfide interchange (EC 1.8.1.8)

Isozymes

Compare fitness of predicted isozymes for: 1.8.1.8

Use Curated BLAST to search for 1.8.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TCS6 at UniProt or InterPro

Protein Sequence (647 amino acids)

>BPHYT_RS25545 hypothetical protein (Burkholderia phytofirmans PsJN)
ASVRIITATDGVAGNTLQIGVEFRYPNGWHGYWRTPGDAGIAPIFDWSRSRNVASASVSW
PAPSRLVISGLQNSVYTGDLILPVSLKLDHPHEATRIALTLDYASCANVCVPEHAEVALT
LPPGMDGPSSEAAAIAAAAQRVPQTPAEAGIGVVHSTLEQTSAGRRLKVDLRSEGTPFLS
PDLFVEGAEAGLPAAPHVHLSNHGHRAALEVELPPAAAAKEPLRLTVVDGSRAAEFMTAS
VVPTGDDGHGIVVILGLALLGGLILNFMPCVLPVLSIKVFSVVKAASTGRKTARRVALAT
ALGIVTSFGLLAAVLSILKLAGASLGWGIQFQQPWFLAGMAVVTTLFAASFFDWLPIGLP
PFLSGGASGATNRGPLVEAFLGGMLSTLLATPCSAPLVGTVVGFALARRPLEITAVLLAL
GVGMALPFLTLVLAPSLATRLPRPGQWMIQLRKIMGLLLLTTSIWLIASLWNIAGMAVAS
LVSIVLIAMLAVRAAETRWGSLRTARWSGAATALLACCAIAISSLPPFGTGDRSAPPTEW
QAFDPNAISALVASGKTVLVDVTASWCLTCKVNELSVLDTAAVRTRLRQDNIVRMRADWS
RYNPGVLAYIQRFGRFGIPLDVVYGPRMPQGQLLPEILQTSTLFHAL