Protein Info for BPHYT_RS25130 in Burkholderia phytofirmans PsJN

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 472 transmembrane" amino acids 26 to 50 (25 residues), see Phobius details amino acids 61 to 84 (24 residues), see Phobius details amino acids 93 to 112 (20 residues), see Phobius details amino acids 118 to 139 (22 residues), see Phobius details amino acids 151 to 174 (24 residues), see Phobius details amino acids 183 to 200 (18 residues), see Phobius details amino acids 267 to 289 (23 residues), see Phobius details amino acids 302 to 323 (22 residues), see Phobius details amino acids 331 to 351 (21 residues), see Phobius details amino acids 357 to 379 (23 residues), see Phobius details amino acids 396 to 418 (23 residues), see Phobius details amino acids 424 to 443 (20 residues), see Phobius details PF12832: MFS_1_like" amino acids 31 to 425 (395 residues), 26.5 bits, see alignment E=5.3e-10 PF07690: MFS_1" amino acids 31 to 343 (313 residues), 154.6 bits, see alignment E=5.1e-49 amino acids 308 to 444 (137 residues), 35.8 bits, see alignment E=7e-13 PF00083: Sugar_tr" amino acids 56 to 453 (398 residues), 170 bits, see alignment E=1.4e-53

Best Hits

KEGG orthology group: K08369, MFS transporter, putative metabolite:H+ symporter (inferred from 100% identity to bpy:Bphyt_5053)

Predicted SEED Role

"Niacin transporter NiaP" in subsystem NAD and NADP cofactor biosynthesis global or NAD regulation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TCJ3 at UniProt or InterPro

Protein Sequence (472 amino acids)

>BPHYT_RS25130 MFS transporter (Burkholderia phytofirmans PsJN)
MSTAYPPRASAAARLERLPFSGYHRTIFIIIAIAFFFDSVDLGTMTFVLGSIKTEFGLST
ATAGLVASASFFGMVIGAAIAGLLADRFGRRPVFQWSMVLWGLASYLCSTAQSVEALIFY
RVLLGFGMGMEFPIAQTLLSEFVPAASRGRLIALMDGFWPLGFITAGVVSYFVLPTFGWR
TEFALLAIPAVFVLIVRRVVPESPRWLEHRGRLSEADKILAEVEVKVMKAAGLSQLRAPV
VLAEPPAAKSTGAFREIWSMAYRRRTIMVWTLWFFALLGFYGLTSWLGALMQQAGFAVTK
SVLYTVLISLGGIPGFICAAWLVERWGRKPTCIASLAGSAVMAYVYGQTALHAQTPTLLI
CAGLAMQFFLFAMWAVLYTYTPELYGTGARATGSGFASAIGRVGSLIGPYVVGVVLPMFG
QGGVFSLGAMCFVIAAAAVWILGIETRGLALETLVSEAVETDARGVLSPARE