Protein Info for BPHYT_RS24025 in Burkholderia phytofirmans PsJN

Annotation: histidine utilization repressor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 227 TIGR02018: histidine utilization repressor" amino acids 2 to 226 (225 residues), 265.6 bits, see alignment E=1.6e-83 PF00392: GntR" amino acids 4 to 66 (63 residues), 71.4 bits, see alignment E=3.9e-24 PF07702: UTRA" amino acids 87 to 222 (136 residues), 81.3 bits, see alignment E=6.4e-27

Best Hits

KEGG orthology group: K05836, GntR family transcriptional regulator, histidine utilization repressor (inferred from 100% identity to bpy:Bphyt_4839)

Predicted SEED Role

"Histidine utilization repressor" in subsystem Histidine Degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TBK1 at UniProt or InterPro

Protein Sequence (227 amino acids)

>BPHYT_RS24025 histidine utilization repressor (Burkholderia phytofirmans PsJN)
MPAYEQIKRYVIRRISEGDWKPGGLIPSETELVKEFGVARMTVSRALRELTTERVLTRVQ
GSGTFVAPQRYESTVLEIRNIADEIAARGHRHSARVLTLEPSDDPQALEALGLASGPAFH
SCIVHSEEGEPIQYEDRYVNPKVFPDYLNQDFTIETPNHYMVRLAPIQRAEFCIYAQKPD
AYVRRHLLMDIGEPCLQLWRRTWVGEDVATSVQLWHPASRFHLAGNV