Protein Info for BPHYT_RS22460 in Burkholderia phytofirmans PsJN

Annotation: phosphonate ABC transporter ATP-binidng protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 TIGR02315: phosphonate ABC transporter, ATP-binding protein" amino acids 8 to 253 (246 residues), 286.1 bits, see alignment E=1.1e-89 PF00005: ABC_tran" amino acids 24 to 184 (161 residues), 112.6 bits, see alignment E=2.4e-36

Best Hits

Swiss-Prot: 89% identical to PHNC_PARXL: Phosphonates import ATP-binding protein PhnC (phnC) from Paraburkholderia xenovorans (strain LB400)

KEGG orthology group: K02041, phosphonate transport system ATP-binding protein (inferred from 100% identity to bpy:Bphyt_4524)

Predicted SEED Role

"Phosphonate ABC transporter ATP-binding protein (TC 3.A.1.9.1)" in subsystem ABC transporter alkylphosphonate (TC 3.A.1.9.1) (TC 3.A.1.9.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TGT6 at UniProt or InterPro

Protein Sequence (301 amino acids)

>BPHYT_RS22460 phosphonate ABC transporter ATP-binidng protein (Burkholderia phytofirmans PsJN)
METIREAIRIERLSKTFSNGRKALDEIDLRVEPGEMVALIGASGSGKSTLLRHIAGFTAS
DAQPSQISILGRPIQQNGRIVREVRSIRRDIGFVFQQFNLVNRLSVESNVLIGALARLPL
WRRLSGRFPRAERALSMAALNEVGIGEHARERAANLSGGQQQRAALARALVQRARIVLAD
EPIASLDPESSRRVMEMLRTLNVEHQLTVLVSLHQVDIAMQYCPRTIALRRGKVVYDGPS
AALTPVLLKKLYGDDARELLDAAPISAEDLDTKTVNGSTPAQSTAPASTRYAFALNPAHS
N