Protein Info for BPHYT_RS21765 in Burkholderia phytofirmans PsJN

Annotation: IclR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 254 PF09339: HTH_IclR" amino acids 11 to 54 (44 residues), 45.7 bits, see alignment 6.9e-16 PF12802: MarR_2" amino acids 14 to 61 (48 residues), 31.7 bits, see alignment 2.1e-11 PF01614: IclR" amino acids 127 to 248 (122 residues), 104.4 bits, see alignment E=6.2e-34

Best Hits

Swiss-Prot: 69% identical to SAUR_CUPNH: Probable transcriptional regulator SauR (sauR) from Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_4381)

Predicted SEED Role

"Transcriptional regulator, IclR family" in subsystem Homogentisate pathway of aromatic compound degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TF87 at UniProt or InterPro

Protein Sequence (254 amino acids)

>BPHYT_RS21765 IclR family transcriptional regulator (Burkholderia phytofirmans PsJN)
MSTSNQSNAAAVRAFRVLETLAEAGSPLSMTELVNALGLPKQTVHRILVQLMDAWLVTRG
AGDRLYECSPRVRMLAVNVLMHAGPAAARHVLLEQLVAKIGETCNLTMLSGNDVVYVDRV
ETEWPLRMHLQPGSHVPLHCSASGKLLLSFLPKDRRERVIETLPLRGYSERTITDRDALR
KELSTTRRRLLAINNQEHLQGLIAIAVPVMLDRNRACAAIAVQAPVGRVTLDDLLAFVPD
LRHAAEETAKTFQE