Protein Info for BPHYT_RS20000 in Burkholderia phytofirmans PsJN

Annotation: serine/threonine protein kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 491 PF06745: ATPase" amino acids 14 to 230 (217 residues), 93.4 bits, see alignment E=3e-30 amino acids 253 to 468 (216 residues), 109.6 bits, see alignment E=3.1e-35 PF13481: AAA_25" amino acids 251 to 366 (116 residues), 27.3 bits, see alignment E=5.2e-10

Best Hits

KEGG orthology group: K08482, circadian clock protein KaiC (inferred from 100% identity to bpy:Bphyt_4017)

Predicted SEED Role

"Circadian clock protein KaiC" in subsystem Cyanobacterial Circadian Clock

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TE82 at UniProt or InterPro

Protein Sequence (491 amino acids)

>BPHYT_RS20000 serine/threonine protein kinase (Burkholderia phytofirmans PsJN)
MTNHESQTSSRSNVETGVPGLDEILGGGLVRGGVYLLEGMAGAGKTILSSQIGFHRVSQG
EKVLYMTLIAESHDKLLGHLKGLSFFDEKAVAQQMLFVSGYHELMKDGLDGFLKLIASSI
YDYRPSLMIIDGFRSAREFSETELSLSKFIHELNALVAAMDCTTLLLAPLSGNEPHPEHT
LVDGLIELNRYSDGMRRAREIEVHKMRARNHLMGKHFFRIAESGLLMFPRLEAQCAAQAG
PVDLKTRLGFALPHLDGLLGGGFAQGSTTTLVGPSGVGKTLLCLQFLAAGVARGERCLYL
GFYEGPQRLIGKAEAVSIGLANAYQDGRLVIQWQPAIELAVDELAATALATVKKIGASRI
VIDGVEGFRDSALRTERFGLFLNALLHQLREACITTLLTEELPLYADPGHARSVRVSALT
ENLVLLRYAETDTGLRRMISVVKQRESAHDTSLRELVISSQGLDVIENPASAASLHAPAG
LSATLQPRRNT