Protein Info for BPHYT_RS19600 in Burkholderia phytofirmans PsJN

Annotation: general secretion pathway protein E

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 495 PF05157: MshEN" amino acids 15 to 89 (75 residues), 31.5 bits, see alignment E=1.7e-11 TIGR02533: type II secretion system protein E" amino acids 22 to 492 (471 residues), 750.4 bits, see alignment E=4.2e-230 PF00437: T2SSE" amino acids 132 to 398 (267 residues), 355.4 bits, see alignment E=1.7e-110

Best Hits

Swiss-Prot: 72% identical to HXCR_PSEAE: Probable type II secretion system protein HxcR (hxcR) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K02454, general secretion pathway protein E (inferred from 100% identity to bpy:Bphyt_3937)

Predicted SEED Role

"General secretion pathway protein E"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T7P3 at UniProt or InterPro

Protein Sequence (495 amino acids)

>BPHYT_RS19600 general secretion pathway protein E (Burkholderia phytofirmans PsJN)
MSPAGATEHGGREAPSAIAARLVPYGFARAGQILVAHQHADSLEVWISERTSDAALSEVA
RNFGAVSIVRLPADELTQAINQAYARQDGSAAQVVGEVEGEVDLSRLMQDIPEVEDLLES
EDDAPIIRMINALLTQAAREQASDIHIEPFETSSVVRFRVDGTLRDVVRPKKALHGALIS
RIKIMAQLDIAEKRLPQDGRITLRVGGRPVDVRVSTLPTGHGERAVLRLLEKDASRLNLE
ALGMASDTLGKFDKLIGRPHGIVLVTGPTGSGKTTTLYAAMSRLETATTNIMTVEDPIEY
DLSGIGQTQVNERIGMTFARALRSILRQDPDVIMIGEIRDLETAQIAVQASLTGHLVLAT
LHTNDAASAVTRLTDMGVEPYLLASSLLGVLAQRLVRRLCPICREERVEEDGSVRYHPVG
CDRCGHSGYAGRRGVYELLLIDDDIRTLVHRNAADAEILAAGRAQGMRTLREDADRWLAS
GLTSLEEVIRVTGGA