Protein Info for BPHYT_RS19310 in Burkholderia phytofirmans PsJN

Annotation: oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 349 PF01408: GFO_IDH_MocA" amino acids 5 to 118 (114 residues), 86.9 bits, see alignment E=1.8e-28 PF02894: GFO_IDH_MocA_C" amino acids 134 to 342 (209 residues), 126.3 bits, see alignment E=1.6e-40

Best Hits

Swiss-Prot: 46% identical to YDGJ_ECOLI: Uncharacterized oxidoreductase YdgJ (ydgJ) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_3878)

MetaCyc: 37% identical to scyllo-inositol dehydrogenase (NADP+) (Bacillus subtilis subtilis 168)
RXN-14347 [EC: 1.1.1.371]

Predicted SEED Role

"Nucleoside-diphosphate-sugar epimerases"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.371

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T7I4 at UniProt or InterPro

Protein Sequence (349 amino acids)

>BPHYT_RS19310 oxidoreductase (Burkholderia phytofirmans PsJN)
MSASLKIGLMGYGFAGATFHAPVIEHCGRASVAAIATSQPERALADYPHTKVVADLDALL
ALDELDCIVIATPNDTHFDLARRTLEAGKHVVVDKPVTLNTADAHTLANIALARSKLFIP
FHNRRWDGDFLTVRDLLASGELGRITQYESHFDRFRPEVRQRWREEASRGGGLLLDLGPH
LIDQALALFGTPQTVSATVRTHRDGAGAPDYVHIQLGYGDFEVVLHASALTALVAPRFTI
HGTRGSYMKYGLDTQEDQLKAGARPGDDGFGAGNAAGVLRVLEGDQEVERELPTRNGDYT
GFYIAVADAIQNGVKFPVSAQDAVDVMTVIELASRSSEEGVRLPFERVR