Protein Info for BPHYT_RS18520 in Burkholderia phytofirmans PsJN

Annotation: LexA family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 191 PF00717: Peptidase_S24" amino acids 68 to 183 (116 residues), 85.7 bits, see alignment E=9.6e-29

Best Hits

Swiss-Prot: 33% identical to LEXA_OPITP: LexA repressor (lexA) from Opitutus terrae (strain DSM 11246 / JCM 15787 / PB90-1)

KEGG orthology group: K01356, repressor LexA [EC: 3.4.21.88] (inferred from 100% identity to bpy:Bphyt_3718)

Predicted SEED Role

No annotation

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.88

Use Curated BLAST to search for 3.4.21.88

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T6T4 at UniProt or InterPro

Protein Sequence (191 amino acids)

>BPHYT_RS18520 LexA family transcriptional regulator (Burkholderia phytofirmans PsJN)
MNDETHLAALRSYWKRHQTFPAMSKLCDVVGLTSTSSIFALIKRLSEAGFLERVEGRIAP
TRRFFGRPVLGAVRAGQPQPEGQEPPELLTIDDYLVDDPNRTVLCRVRGESMRDVGLLDG
DLVVVEKNRPTRPGDIVVAVVDGEMTVKTLRLDKNGAYYLEPANQDFQVIRPQGSLEIVG
VVVGSVRKYGR