Protein Info for BPHYT_RS17760 in Burkholderia phytofirmans PsJN

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 255 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details amino acids 46 to 71 (26 residues), see Phobius details amino acids 83 to 105 (23 residues), see Phobius details amino acids 151 to 176 (26 residues), see Phobius details amino acids 195 to 215 (21 residues), see Phobius details amino acids 235 to 254 (20 residues), see Phobius details TIGR00056: ABC transport permease subunit" amino acids 6 to 254 (249 residues), 276.2 bits, see alignment E=1.5e-86 PF02405: MlaE" amino acids 41 to 252 (212 residues), 249.3 bits, see alignment E=1.5e-78

Best Hits

Swiss-Prot: 63% identical to MLAE_HAEIN: Intermembrane phospholipid transport system permease protein MlaE (mlaE) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K02066, putative ABC transport system permease protein (inferred from 100% identity to bpy:Bphyt_3570)

Predicted SEED Role

"Uncharacterized ABC transporter, permease component YrbE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T6X7 at UniProt or InterPro

Protein Sequence (255 amino acids)

>BPHYT_RS17760 ABC transporter permease (Burkholderia phytofirmans PsJN)
MISAIGRSVIGGLGTAGYATRFFFRLLLEFFPLLRRPRLVTKQIHFVGNYSLVIIAVSGL
FVGFVLGLQGYYTLNRYGSEQALGLLVALSLVRELGPVVTALLFAGRAGTSLTAEIGLMK
AGEQLTAMEMMAVDPVKVVVAPRLWAGIISMPILAAIFSAVGVFGGYVVGVLLIGVDAGA
FWSQMQGGVDVWRDVGAGVIKSVVFGLAVTFVALFQGYEAKPTPEGVSRATTKTVVYASL
AVLGLDFLLTALMFS