Protein Info for BPHYT_RS16950 in Burkholderia phytofirmans PsJN

Updated annotation (from data): 2-dehydro-3-deoxygalactonokinase DgoK (EC 2.7.1.58)
Rationale: specifically important for D-galactose utilization
Original annotation: 2-dehydro-3-deoxygalactonokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF05035: DGOK
  • amino acids 32 to 334 (303 residues), 334.2 bits, E=2.6e-104

Best Hits

KEGG orthology group: K00883, 2-dehydro-3-deoxygalactonokinase [EC: 2.7.1.58] (inferred from 100% identity to bpy:Bphyt_3414)

Predicted SEED Role

"2-dehydro-3-deoxygalactonokinase (EC 2.7.1.58)" in subsystem D-galactonate catabolism (EC 2.7.1.58)

MetaCyc Pathways

• D-galactonate degradation (3/3 steps found)
• L-glucose degradation (3/7 steps found)

KEGG Metabolic Maps

• Galactose metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.58

Sequence Analysis Tools

See B2SYR9 at UniProt or InterPro

Protein Sequence (350 amino acids)

>BPHYT_RS16950 2-dehydro-3-deoxygalactonokinase DgoK (EC 2.7.1.58) (Burkholderia phytofirmans PsJN)
MKRAGSPTQAAGHAAAVAVDASHEHAALIALDWGTTSLRAYLYDASGNVLATRASTAGIM
NLPRSAEQGGFDAAFDDTCGAWLAHAPAAPVIAAGMVGSAQGWLEAPYVDTPASADALVA
GIVRVKAACGVTLHIVPGVLQRGELPNVMRGEETQIFGALGEETNTADSGKRSLIGLPGT
HAKWAVVQADRIERFHTFMTGEVFAALREHTILGRTMLTPDSPDTSAFLHGVNIAREKGQ
AGVLATVFSSRTLGLTGQLSREQQPDYLSGLLIGHELAGLDAVLAQQQSALAGQSLRLIG
NEALCERYRLALAQFGCTQAELVKHATERGLWRVASQAGLVKPAAKTARA