Protein Info for BPHYT_RS13375 in Burkholderia phytofirmans PsJN

Annotation: permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 456 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 32 to 54 (23 residues), see Phobius details amino acids 61 to 83 (23 residues), see Phobius details amino acids 104 to 133 (30 residues), see Phobius details amino acids 143 to 161 (19 residues), see Phobius details amino acids 181 to 201 (21 residues), see Phobius details amino acids 234 to 257 (24 residues), see Phobius details amino acids 271 to 293 (23 residues), see Phobius details amino acids 308 to 330 (23 residues), see Phobius details amino acids 338 to 362 (25 residues), see Phobius details amino acids 367 to 390 (24 residues), see Phobius details amino acids 396 to 419 (24 residues), see Phobius details amino acids 431 to 453 (23 residues), see Phobius details PF02447: GntP_permease" amino acids 9 to 453 (445 residues), 531.7 bits, see alignment E=1.4e-163 TIGR00791: transporter, gluconate:H+ symporter (GntP) family" amino acids 10 to 456 (447 residues), 485.2 bits, see alignment E=1e-149 PF03600: CitMHS" amino acids 28 to 402 (375 residues), 52.4 bits, see alignment E=4.6e-18

Best Hits

Swiss-Prot: 49% identical to GNTP_ZYMMO: Gluconate permease (gntP) from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)

KEGG orthology group: K03299, gluconate:H+ symporter, GntP family (inferred from 100% identity to bpy:Bphyt_2702)

Predicted SEED Role

"Gluconate transporter family protein" in subsystem D-gluconate and ketogluconates metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2SY18 at UniProt or InterPro

Protein Sequence (456 amino acids)

>BPHYT_RS13375 permease (Burkholderia phytofirmans PsJN)
MATVQGSLLLVYALIAIIALVVLIARFKMNPFITLMVVSVALALAVGMPATSILKSFETG
VGGTLGHIAIVVGLGTMLGKMMAESGGAERIARTLIDLFGPKNVHWAMMCIAFLVGLPVF
FEVGFVLLIPIAFNVAQRTGTSMIRVGIPMVAGLSVVHGLIPPHPAALLAVTAYNADIGH
TIFYALIVGIPTAAIAGPLFSKLIARFVVLDGVNPMAQQFIEQDAKRSHQELPGFGITLL
TVLLPVLLMLVGSWADLIVPAKSTANNVLRLIGHPDMALLLAVLLSFITFGKARGFNRDQ
ILKFTNECLAPTASITLVVGAGAGFGRILIDSGASKAIVDVATGAHVPLLILAWLVAALI
RVATGSATVAMATAAGIIAPIAAAAASTVGGVRPELLVLATGAGSLILSHVNDGGFWLVK
EYFGMTVPQTFKTWTVCETIISVTALLLTLGLSTVI