Protein Info for BPHYT_RS13290 in Burkholderia phytofirmans PsJN

Annotation: cysteine ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 225 transmembrane" amino acids 16 to 46 (31 residues), see Phobius details amino acids 58 to 79 (22 residues), see Phobius details amino acids 91 to 95 (5 residues), see Phobius details amino acids 187 to 207 (21 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 13 to 110 (98 residues), 103 bits, see alignment E=5.3e-34 PF00528: BPD_transp_1" amino acids 34 to 215 (182 residues), 85.2 bits, see alignment E=2.4e-28

Best Hits

Swiss-Prot: 54% identical to YECS_ECOL6: L-cystine transport system permease protein YecS (yecS) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K02029, polar amino acid transport system permease protein (inferred from 98% identity to bgf:BC1003_1077)

MetaCyc: 54% identical to cystine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"Cystine ABC transporter, permease protein"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2SY01 at UniProt or InterPro

Protein Sequence (225 amino acids)

>BPHYT_RS13290 cysteine ABC transporter permease (Burkholderia phytofirmans PsJN)
MPAWLHLMAQSLWPLLYAGLVFTVPLTLISFAIGLALAFLVALVRLFGPKWAVAIVRFYV
WLFRGSPLLVQLFVIFYGLPNVGIVLDPLTAAIIGFSLNVGAYNSEVIRGVIESIPKGQW
EAAYSMGMTREQALRRAILPQAARVALPPLSNSFIALVKDTSLAAVLTVPEVFQAAQRIA
SVTYEPLILYTEAALVYLVFSSVLSSAQVRLERKFGRHALFQAGN