Protein Info for BPHYT_RS11375 in Burkholderia phytofirmans PsJN

Annotation: acriflavin resistance protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1042 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details amino acids 343 to 362 (20 residues), see Phobius details amino acids 369 to 388 (20 residues), see Phobius details amino acids 397 to 419 (23 residues), see Phobius details amino acids 433 to 459 (27 residues), see Phobius details amino acids 472 to 495 (24 residues), see Phobius details amino acids 539 to 559 (21 residues), see Phobius details amino acids 872 to 890 (19 residues), see Phobius details amino acids 897 to 918 (22 residues), see Phobius details amino acids 924 to 945 (22 residues), see Phobius details amino acids 970 to 989 (20 residues), see Phobius details amino acids 999 to 1021 (23 residues), see Phobius details PF00873: ACR_tran" amino acids 16 to 1021 (1006 residues), 518.7 bits, see alignment E=1.5e-159

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_2293)

Predicted SEED Role

"Acriflavin resistance protein" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T531 at UniProt or InterPro

Protein Sequence (1042 amino acids)

>BPHYT_RS11375 acriflavin resistance protein (Burkholderia phytofirmans PsJN)
MSTPHEEGRFNLSAWALRHQALVVFLIALATAFGILAYTRLAQSEDPPFTFRVMVIRTFW
PGATARQVQEQVTDRIGRKLQETPAIDFVRSYSRPGESLMFFSMKDSAPVKDVPETWYQV
RKKVGDIAATLPQGIQGPFFNDEFGDVYTNIYTLEGDGFSPAQLHDYADQLRTVLLRVPG
VAKVDYFGDPDQHIYIEIANTQLTRLGISPQQLGQAINSQNSVSQAGTLTTADDRVFVRP
TGQFKDVNALADTLIRINNRSFRLGDIATIKRGYDDPVVTQMRAGGKAVLGIGVTMQPGG
DVIRLGKALDQQMAQLRKALPAGLQLVEVSSMPDAVARSVDDFLEAVAEAVAIVLVVSLV
SLGLRTGMVVVISIPVVLAVTALCMYLFDIGLHKVSLGTLVLALGLLVDDAIIAVEMMSV
KLEQGWNRTRAAAYAYTSTAFPMLTGTLVTVSGFLPIALAKSSTGEYTRSIFEVSAIALI
ASWLAAVVLIPLLGYHLLPERKREAHEAHLPDDHEHDIYDTRFYRRLRGWIGWCIERRFV
VLAITVALFALAMAGFTLVPQQFFPSSDRPELLVDVRLPEGASFEATLRQAQRLEKALVG
RPEIDHTVDFVGTGAPRFYLPLDQQLPQPNFAQFVITAKSVKDREKLAQWLEPELRNNFP
AIRTRLSRLENGPPVGYPVQFRVSGDDIATVRSIAERVAATLRADRGTRNVQFDWDEPAE
RSVRFEVDQKKARELGVSSDDISSFLAMTLSGYTVTQYRERDKLISVDLRAPKAERVDPA
QLVTLAMPTPNGPVPLGTLGHLRNDLEYGVIWERDRQPTLTVQSDVAPGAQGIDVTHAVD
KALGPIRAALPVGYRIEIGGSVEESGKGQTSINAQMPIMIIAVLTLLMIQLQSFARVLMV
VLTAPLGLIGVVLTLLLFGQPFGFVAMLGVIAMFGIIMRNSVILVDQIEQDIASGHKRFD
AIVGATVRRFRPITLTAAAAVLALIPLLRSNFFGPMATALMGGITSATILTLFYLPALYA
VSFRVRADEREPQTSGPKHTGN