Protein Info for BPHYT_RS11285 in Burkholderia phytofirmans PsJN

Annotation: LacI family transcription regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 362 PF00356: LacI" amino acids 13 to 59 (47 residues), 44.9 bits, see alignment 1.2e-15 PF00532: Peripla_BP_1" amino acids 72 to 219 (148 residues), 46 bits, see alignment E=7.6e-16 PF13377: Peripla_BP_3" amino acids 180 to 360 (181 residues), 53.1 bits, see alignment E=6.4e-18

Best Hits

KEGG orthology group: K02525, LacI family transcriptional regulator, kdg operon repressor (inferred from 100% identity to bpy:Bphyt_2275)

Predicted SEED Role

"2-ketogluconate utilization repressor PtxS" in subsystem 2-Ketogluconate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T514 at UniProt or InterPro

Protein Sequence (362 amino acids)

>BPHYT_RS11285 LacI family transcription regulator (Burkholderia phytofirmans PsJN)
MSTTPQAAPRRATITDVAREAGTGKTSISRYLNGEMSVLSPELRARIEAAIARLDYQPNQ
MARGLKRGRNRLIGMLLADLTNPYTVEVLQGVEAACHALGLMPLICHAANEVEMERRYLQ
LLTTYRVEGVIVNALGVREETLRPVGGGGIPAVLVDRSVDGLVTDMVGLDNRAAAELGTR
HLLDNGFDEIWFVVQPFEQVSSRQLREAAFREAMSAQGEQRGKSAARGHTLVLNLADADE
VARSLAELDRAIDAAAQASDAAAATGNAARIALFAANAPVALCLALHLKARYGADWQARV
ALLSIDDPDWAELTGVTTIRQPTYEIGYRAVEFLHERIEGVQTIARDCLLPGELIVRAST
LR