Protein Info for BPHYT_RS08985 in Burkholderia phytofirmans PsJN

Annotation: Rrf2 family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 166 TIGR00738: Rrf2 family protein" amino acids 1 to 134 (134 residues), 102.7 bits, see alignment E=7.1e-34 PF02082: Rrf2" amino acids 3 to 134 (132 residues), 116.1 bits, see alignment E=2e-37

Best Hits

Swiss-Prot: 48% identical to NSRR_BACLD: HTH-type transcriptional regulator NsrR (nsrR) from Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)

KEGG orthology group: K13771, Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor (inferred from 100% identity to bpy:Bphyt_1812)

Predicted SEED Role

"Nitrite-sensitive transcriptional repressor NsrR" in subsystem Nitrosative stress or Oxidative stress or Rrf2 family transcriptional regulators

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T3Q9 at UniProt or InterPro

Protein Sequence (166 amino acids)

>BPHYT_RS08985 Rrf2 family transcriptional regulator (Burkholderia phytofirmans PsJN)
MRLTDYTDYSLRVLLYLAVRGGGLSTIQDISDAYGISKNHLMKVVQQLGELGWVETVRGR
NGGLRLAEQTNALTVGEIVRATESDFALVGCFPDQHGERRGCVITAQCRLRGALEAARNA
FLTELDRHTIGEVAQPHGPLAALLGLSQVIPITPVANTSDGSTSAA