Protein Info for BPHYT_RS08160 in Burkholderia phytofirmans PsJN

Annotation: membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 166 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 30 to 51 (22 residues), see Phobius details amino acids 59 to 80 (22 residues), see Phobius details amino acids 94 to 117 (24 residues), see Phobius details amino acids 143 to 162 (20 residues), see Phobius details PF01478: Peptidase_A24" amino acids 9 to 112 (104 residues), 64.1 bits, see alignment E=7.4e-22

Best Hits

KEGG orthology group: K02278, prepilin peptidase CpaA [EC: 3.4.23.43] (inferred from 100% identity to bpy:Bphyt_1650)

Predicted SEED Role

"Probable prepilin peptidase transmembrane protein"

Isozymes

Compare fitness of predicted isozymes for: 3.4.23.43

Use Curated BLAST to search for 3.4.23.43

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T399 at UniProt or InterPro

Protein Sequence (166 amino acids)

>BPHYT_RS08160 membrane protein (Burkholderia phytofirmans PsJN)
MNVSVGIFLFIAWAAVVAIGDCRRRRISNSVVLAGLAAAFCCALFQCGPFGISLTQSGIG
ALIGLAALLPFFALGVMGAADVKVFAVLGAWCGMHALLGLWMAASLAASVHALWLLITTR
TRLASLARQPGATFELAGKASTPYAACLAVAASGWLVVHGMAGSVR