Protein Info for BPHYT_RS07945 in Burkholderia phytofirmans PsJN

Annotation: small mechanosensitive ion channel protein MscS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 876 transmembrane" amino acids 49 to 71 (23 residues), see Phobius details amino acids 220 to 241 (22 residues), see Phobius details amino acids 269 to 288 (20 residues), see Phobius details amino acids 300 to 321 (22 residues), see Phobius details amino acids 341 to 358 (18 residues), see Phobius details amino acids 368 to 391 (24 residues), see Phobius details amino acids 416 to 438 (23 residues), see Phobius details amino acids 450 to 471 (22 residues), see Phobius details amino acids 491 to 512 (22 residues), see Phobius details amino acids 532 to 553 (22 residues), see Phobius details amino acids 583 to 605 (23 residues), see Phobius details amino acids 612 to 639 (28 residues), see Phobius details PF21088: MS_channel_1st" amino acids 586 to 627 (42 residues), 32.2 bits, see alignment 8.6e-12 PF00924: MS_channel_2nd" amino acids 629 to 694 (66 residues), 58.7 bits, see alignment 4.9e-20

Best Hits

KEGG orthology group: K03442, small conductance mechanosensitive channel (inferred from 100% identity to bpy:Bphyt_1608)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T357 at UniProt or InterPro

Protein Sequence (876 amino acids)

>BPHYT_RS07945 small mechanosensitive ion channel protein MscS (Burkholderia phytofirmans PsJN)
MQSCPSRRESEAAPSNGGQPATHAAFHFSSDRSACGARHGARPPLAARFAAWAAAVFVAL
ILCVGLLPANAFAAGAATSTPVIPALQSLINSATVSATPASSASGASAAEAASAPSPASQ
AELAHSLDSVISTLDNDRQRTALVAQLKKLRDVSKNVAPPAPAQPSPGLLGAIASGIASF
ESDVHQGRTPVRYWGGRFNAAGNELYTIISGQGHESFGRILFSMAAMLAGWGACAGALIY
VQHRLYRRFGIVMGLQPNPTTRELLIFALRRVGPWIIAFVAALLFVRAMPDALGRTLGMV
VAYAIVAGAVFSAICLIMFSLFGSGHRRIAVRLLIDHARRVLFVVGVCGALGDAAVNYDV
AHQLGSNLAALISTAANMTAAVLTGYFALAFRRPVAHLIRNRPYEQRTNHKAATDAFDVL
AALWHVPVLVLATASVVATLGGSGSSENVLQISVVTAALLVLAFFLSAVVLRLTRPRSAR
TRRRSPYLTRLLRFFGTLLTLFIWLFFFELAARLWGVSLAAVVEESVAARGIAHAVTAIV
ATVFIAWLLWILVDTAITEALNPAGPRNKARAPSMRARTMLPLVRNVLLVSIMTIAGIVT
AANLGINVTPLLAGAGVIGLAIGFGAQSLVTDLITGLFIIIEDTISVGDWIDVDGGHAGT
VEHLSIRTVRLRDGQGAIHAIPFSQIKIVKNLSRDFAYAVFEVRMSFTTDVDQITQLIRE
VGADLMADFRYRREMLGPIEVWGLDRFDPNWMVVKGQIKTRPLQQWSVARAFNLRLKRKM
DEAGIEIPVPQMRVYTSSKDSEGQPLQDDEVSGIALHPHEHEHAQVGAASAARAVHAPLA
VARDVSHEPRPAPPPTGQTAPIPPQIPTAGEAGGKS