Protein Info for BPHYT_RS07685 in Burkholderia phytofirmans PsJN

Updated annotation (from data): ABC transporter for L-Arginine, putative ATPase component
Rationale: This is presumably the ATPase component but lacks fitness data.
Original annotation: histidine ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 263 PF00005: ABC_tran" amino acids 27 to 187 (161 residues), 126.1 bits, see alignment E=1.6e-40 PF13304: AAA_21" amino acids 153 to 217 (65 residues), 31.3 bits, see alignment E=2.1e-11

Best Hits

Swiss-Prot: 72% identical to HISP_PSEAE: Histidine transport ATP-binding protein HisP (hisP) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K10017, histidine transport system ATP-binding protein [EC: 3.6.3.21] (inferred from 100% identity to bpy:Bphyt_1556)

Predicted SEED Role

"Histidine ABC transporter, ATP-binding protein HisP (TC 3.A.1.3.1)" in subsystem Arginine and Ornithine Degradation (TC 3.A.1.3.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.21

Use Curated BLAST to search for 3.6.3.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T308 at UniProt or InterPro

Protein Sequence (263 amino acids)

>BPHYT_RS07685 ABC transporter for L-Arginine, putative ATPase component (Burkholderia phytofirmans PsJN)
MLHTTQTEACKLAVQDIHKRYGDNEVLKGVSLNANKGDVISIIGASGSGKSTFLRCINFL
ERPNAGQIVVDGEMVKTKTDRAGNLEVADHKQLQRIRTKLAMVFQHFNLWAHMNVLENIV
EAPIHVLGLKRKEAEDRAREYLEKVGLAPRLEKQYPSHLSGGQQQRVAIARALAMNPDVM
LFDEPTSALDPELVGEVLKVMQKLAEEGRTMIVVTHEMGFARNVSNHVMFLHQGRTEEEG
LPAEVLSAPRSERLKQFLSGSLK