Protein Info for BPHYT_RS06190 in Burkholderia phytofirmans PsJN

Annotation: heptosyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 375 transmembrane" amino acids 33 to 52 (20 residues), see Phobius details PF01075: Glyco_transf_9" amino acids 98 to 296 (199 residues), 89.1 bits, see alignment E=1.5e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_1257)

Predicted SEED Role

"Heptosyltransferase family protein, lipopolysaccharide core biosynthesis" in subsystem LOS core oligosaccharide biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T261 at UniProt or InterPro

Protein Sequence (375 amino acids)

>BPHYT_RS06190 heptosyltransferase (Burkholderia phytofirmans PsJN)
MSRLAGRLRIFARAIPRLLIKPLRREPRHPRRILIAHHLLLGDTLLLTPLLAKLREQYPQ
AQIVLTCPKAIVPLYAGRPFDVTALPFDPRDSKSVRNVLLSGPYDIGMVLGDNRHSWLAL
GAGCRWIIGHAGDRPAWKNWPLNRSLPYPDTAAAWADLATELIDGPPPRAYRPADWRAPQ
HAALPEPSLLTKPYVVLHPGASTSVKRWPNARWRELAQRVEALGYLPVWTGGPGEAELIR
AIDPEPHHPNLAARLGLGELWHLFAGAQAVVCPDTGVAHLGRLIGVPTLALFGPGNAAIH
GAGRYWREVPFVPITIADMPCRDQPFIFRREVAWVRRCDRNETTCVAWRGDHADCMGRLS
VESVYNALQNVLVKV