Protein Info for BPHYT_RS03290 in Burkholderia phytofirmans PsJN

Annotation: LPS-assembly protein LptD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 788 signal peptide" amino acids 1 to 40 (40 residues), see Phobius details PF04453: LptD" amino acids 315 to 689 (375 residues), 337.9 bits, see alignment E=5.3e-105

Best Hits

Swiss-Prot: 95% identical to LPTD_PARXL: LPS-assembly protein LptD (lptD) from Paraburkholderia xenovorans (strain LB400)

KEGG orthology group: K04744, LPS-assembly protein (inferred from 100% identity to bpy:Bphyt_0675)

Predicted SEED Role

"Outer membrane protein Imp, required for envelope biogenesis / Organic solvent tolerance protein precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2SX60 at UniProt or InterPro

Protein Sequence (788 amino acids)

>BPHYT_RS03290 LPS-assembly protein LptD (Burkholderia phytofirmans PsJN)
MPPRQLSQTTPSCAVVPRKRRLVAALIAVPGLMPALAHAQLVGEAAQPQPIDAPWGMQLA
PQLEDRPLQTGQKPATFVLGDATTGTSDQDMAAKGSAEVRRNTVVIKADALHYDQDTDMA
DAYGKVHVVNNGNSFVGPEAHMRVDSSEGFMTAPKYHFNVTGGSGSAERVDLLDNERSVF
TKGTYTACACADDPAWYIKGSEFDFDTGADEGVAHNGVLFFQGVPVFASPWLSFPLSGQR
RSGVLPPTFSLSSSNGFELSVPYYFNIAPNRDLTVTPRLISKRGVQLQSTFRYLSPTYSG
SITGEFLPDDHLTKTNRYALYIQHNQNFGNGFGGYIYYNKVSDNTYPEDLSSSVSQFMNG
TQLLYQQEAGLTYSNGPWSVLAREQHWQTLEPSTAPYGREPQLNVKYAKYNVGGFDYGAE
ADYTNFSITTADQTEGQRVMFNPYLAYSVVGPGYFVTPKVQWHFASYNLRNIHDDVPLGT
PKNFTESIPTFTFDTGLIFDRSVRIFGQDYIQTLEPRLYYVYTPYRNQESAPLFDTADSD
FGLAEIFTPNTFVGNDRIADANRLTAALTTRFIDAATGDERARFVIAQQYYFQDQRVTLQ
PTQTSTQATHSDLIAGASFKLGAGFASETAFQYNADNNQLVKTSIGFGFSPATGKVINVG
YRYTRANTTLDNQPINQVLISGQWPLTHRVFGVGRFNYDLGGHRIVDGLVGLQYDADCWT
LGAGIQRYANGLNTSGQNQSSTRFLAQLTFKGLSSVDNGLMSAFRASVAGYTPLPPPPPP
ESRFTNYE