Protein Info for BBR_RS19915 in Bifidobacterium breve UCC2003

Annotation: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 339 PF00590: TP_methylase" amino acids 52 to 253 (202 residues), 97.5 bits, see alignment E=5.5e-32 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase" amino acids 54 to 317 (264 residues), 206.8 bits, see alignment E=2.1e-65

Best Hits

KEGG orthology group: K07056, (no description) (inferred from 94% identity to bln:Blon_2430)

Predicted SEED Role

"rRNA small subunit methyltransferase I" in subsystem Heat shock dnaK gene cluster extended

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (339 amino acids)

>BBR_RS19915 16S rRNA (cytidine(1402)-2'-O)-methyltransferase (Bifidobacterium breve UCC2003)
MTSADELNEQRDAEQSVAQVFERNDGNDGIDAGEPAASQTRESAVTIPAGTVVLAATPIG
NVGDASARLVAFLERADIVAAEDTRRLFDLARRLGVYVNGRVVAYHDHNERDKADGLLDQ
VETGATVLVVSDAGMPTINDPGLAIVRRAIERGLPVTCAPGPSAVLDALALSGLPTDRFC
YEGFLPRKHAERVQYLRTLLGERRTIVFYETPHRIADSMDDLLDAFGPNRPMALCRELTK
DYEQIRRGPIGEIRQSVIDDPPRGEMVLVIGGASSEEAEAAAPSTLSVEDMAVLAIDRAL
EDGLRIKDAIAQVVQEHPLADGSLANRKQVYAAVLEIKG