Protein Info for BBR_RS19710 in Bifidobacterium breve UCC2003

Annotation: FAA hydrolase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 273 PF10370: Rv2993c-like_N" amino acids 1 to 60 (60 residues), 44.4 bits, see alignment E=2.5e-15 PF01557: FAA_hydrolase" amino acids 65 to 271 (207 residues), 205.9 bits, see alignment E=6.2e-65

Best Hits

KEGG orthology group: None (inferred from 96% identity to bln:Blon_2375)

Predicted SEED Role

"Fumarylacetoacetate hydrolase family protein" in subsystem Gentisare degradation or Salicylate and gentisate catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (273 amino acids)

>BBR_RS19710 FAA hydrolase family protein (Bifidobacterium breve UCC2003)
MRLARFSLNDSPRYAFVQRDETDGKDYLIELDGHPLAGDQVAPTGNRYPVDGDGIRLLSP
VIPSKVYGLAKNYEAHAQFMHEAGHSEIAHAPENMVIFTKPSTSVIGPDDPIVYPACSKD
MNFEPEVAVVMGRIAKNVSVENVMDYVLGFTCVNDVTLRDLQGIDPTWTRAKGFDTSCPL
GPWIVMRDDLNWKDAEISFTLNGEDVPMASGTTANLIHGIPEQIAAISSFSTLLPGDVIM
TGTPNASGHLDPGDETIVHVEGIGDLRNVIVRA