Protein Info for BBR_RS19690 in Bifidobacterium breve UCC2003

Annotation: glycerophosphodiester phosphodiesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03009: GDPD
  • amino acids 113 to 352 (240 residues), 81.9 bits, E=4e-27

Best Hits

KEGG orthology group: None (inferred from 92% identity to blb:BBMN68_1512)

Predicted SEED Role

"Glycerophosphoryl diester phosphodiesterase (EC 3.1.4.46)" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization (EC 3.1.4.46)

MetaCyc Pathways

• glycerophosphodiester degradation (1/2 steps found)
• phosphatidylcholine resynthesis via glycerophosphocholine (1/2 steps found)
• phospholipid remodeling (phosphatidylethanolamine, yeast) (2/4 steps found)
• glycerol and glycerophosphodiester degradation (1/4 steps found)
• anandamide biosynthesis I (2/12 steps found)

KEGG Metabolic Maps

• Glycerophospholipid metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.4.46

Protein Sequence (369 amino acids)

>BBR_RS19690 glycerophosphodiester phosphodiesterase (Bifidobacterium breve UCC2003)
MSSKLWRNVVLAGVAAAGAAVWAVAPRTFNDKRRNFVPSIPEVWYAHRGLHDAGSGLVNV
ADIADYAGDNPVSAQSDTTGQSIAENDDYVALARAMAIKAGYGSADTTGPIAPENSLAAF
AAACEAGYGIELDVQLTLDGQVVVVHDADLLRVAGDSRLIEDLTYDELTRIPLFPNGKSG
DLKAEPLPGAGENPPLVVTPSAAPEGYYQHVPLFSDVLDVVAGRAPLIVEYKFSNNRAWD
ERSEELMEKGHALLEAYDGPYVVESFHPGAVNWYKEHHPEVCRGQLSWPAKLDKHGAAEW
TAGLLAFNWLSRPDFVAYDWTGGASPQVKLARSMGATAVSWTVRSSEELAQCEPYFDRHI
FEAFVPDEV