Protein Info for BBR_RS18615 in Bifidobacterium breve UCC2003

Annotation: DUF4037 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 733 transmembrane" amino acids 608 to 628 (21 residues), see Phobius details PF13424: TPR_12" amino acids 139 to 212 (74 residues), 43 bits, see alignment E=8.7e-15 PF13228: DUF4037" amino acids 528 to 630 (103 residues), 101.6 bits, see alignment E=7.3e-33

Best Hits

Predicted SEED Role

"FOG: TPR repeat"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (733 amino acids)

>BBR_RS18615 DUF4037 domain-containing protein (Bifidobacterium breve UCC2003)
MADEEALLKQFAAQFAHGPNDADDTDAAAAAQHANNPENQAATNAEQSSTSFDTQQFLNG
LDAIFDRHAAATEAGPYLEQAMVDAENAGDEAGLLTVLNETMGFYRSQGRHKDNQWIVQR
ALELAARMGLTTGTSEAWATTLINCATAMRAAKQYDQAEDLYHQAQDVCRHSLAPTDRRL
AALHNNLSMLYSETNRPDKAELELREALRIIEASSVNPNEDIDVASSHTNLALTLLTEHK
LEGAHWHAAKALDIYKTGHLEHSAHYASALAGYAQVCFAEKRYADAVAGYRHALDVIEEC
YGKDTDYWRITEDNLRQAETQAQAAGIDIVPNDTTDATTAPTQQAANAEAASQYSTDAPV
MPTAPVSDSTATATPAVGISGLKLARAFWTQVGKPMIAAKYPQYVARIAAGLVGHGSECY
GFDDAYSQDHDFGPRFCLWLSDEDYTAIGEQLQTDYDALPRDFSIDAQGHAVFSTNTSAI
ATDHGTPSPITPRAQGVNRRDGVFRIGDFFESITGYRTAPAQTSPHEWLMLDEATLAAAT
NGEVFADPTGQFSKTRQGFKDMPDDVRLALISKRLGMIAQAGQYNLPRSLKRGDGAAAWL
SIHEFVNAASSLVFLINVPMVAGYLPYYKWQFAALRKLSKSMFALLPDVAEQLESVMRLS
SAACYGGAGFGEGGKGSAPAIDQINGIVEHIAAEIVKELQREHLTTSTETFLEWQRPYIE
DHIASDDPVLKSL