Protein Info for Ac3H11_932 in Acidovorax sp. GW101-3H11

Annotation: Probable Co/Zn/Cd efflux system membrane fusion protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 411 signal peptide" amino acids 1 to 53 (53 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 62 to 383 (322 residues), 243.3 bits, see alignment E=1.6e-76 PF16576: HlyD_D23" amino acids 73 to 289 (217 residues), 64.5 bits, see alignment E=1.7e-21 PF13533: Biotin_lipoyl_2" amino acids 93 to 135 (43 residues), 37.4 bits, see alignment 3.4e-13 PF13437: HlyD_3" amino acids 197 to 290 (94 residues), 51.8 bits, see alignment E=2.5e-17

Best Hits

KEGG orthology group: None (inferred from 73% identity to dia:Dtpsy_1125)

Predicted SEED Role

"Probable Co/Zn/Cd efflux system membrane fusion protein" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165JSI5 at UniProt or InterPro

Protein Sequence (411 amino acids)

>Ac3H11_932 Probable Co/Zn/Cd efflux system membrane fusion protein (Acidovorax sp. GW101-3H11)
VLRVLFRRFFLVALFFTGFPMRTPSALRPLQRHSRFLLVLATASLLAACSRPAPPEEPVR
SVKLLTVGVGALQSSLEYSGEVRARVESRLGFRVAGKIVKRQAELGQHVKAGQVLAQLDP
KDYQLATDAARAQLASATTQRDLAAADLKRYQTLKDQNFISGAELERREATLKAAQATLD
QARAQLSSQGNQAAYTTLVADVSGVVTGIDAEPGQVVAAGTPVVRIAQDGPRDVVFVVPE
DKVAQMAVGSEVAVRGWSGGATLAGAVREVAASADAATRTFQVKVAIDGAEAPALGATVY
VTPKALSHAGIPAIKLPTSALRQEGQATAVWVYDPASSTVKSQPVQIATADGNEAVVAAG
LAPGMQVVATGVHVLSPGQKVMVYQPKTASPPAGKAKAAPELVANPASAAN