Protein Info for Ac3H11_4988 in Acidovorax sp. GW101-3H11

Annotation: Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 PF00501: AMP-binding" amino acids 14 to 430 (417 residues), 224.2 bits, see alignment E=2.5e-70 PF23562: AMP-binding_C_3" amino acids 466 to 599 (134 residues), 47.2 bits, see alignment E=2.9e-16

Best Hits

KEGG orthology group: None (inferred from 83% identity to adk:Alide2_4261)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165JJ07 at UniProt or InterPro

Protein Sequence (600 amino acids)

>Ac3H11_4988 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Acidovorax sp. GW101-3H11)
MSTLPDLTLPQMLRERARTDAQRIAIRQKDFGIWKPFTWAQYHQRASHFGLGLKALGLPA
GGHVGVISENRIEWVLAQMGAGLVGAVTVGVYPTSPTNEVAYVVGHADIEIMVCEDQEQT
DKLLAALPDLPRLKKIVVMETKGLRSFAPEVRQFIATFDEVEQLGAASGQQAIIDDALAR
QRLDDVGLMIYTSGSTGKPKGAMISYRNIRGVVPGIVDRLELSRDTTHLSYLPLCHVAEQ
MLTSFVPVYLGSQVNFGESIRTVQEDLREVAPTMFLGVPRIWEKLHAAIHIKLQETGGLR
RTLFHKAYNACKPLAEKPHSNWSAGDKLTYAASYWLVFRALQNFIGLRNAHVALTGAAPI
PPDVVRFFRVLGVPLIEVYGLTESTGMVTGHRLDHVVVGTVGVPTQGVEHRIADNGELQI
KGEMVFAGYYKNPEATASSIVDGWLHTGDVVREEHDQIKIVDRLKDIMITAGGKNLTPSE
IENTMKGSPFIKECIIVAEARKFVGALVMIDYETVGKWAEARRIPFTHYRSLVEHPEVRG
LIDAEINQGNQRLAQVSQIRKFHLLTKELDHDDGEVTATMKVRRTSIYKTYAAEIEALYG