Protein Info for Ac3H11_4846 in Acidovorax sp. GW101-3H11

Annotation: Transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 303 TIGR03298: transcriptional regulator, ArgP family" amino acids 5 to 300 (296 residues), 351.9 bits, see alignment E=1.2e-109 PF00126: HTH_1" amino acids 8 to 64 (57 residues), 68.4 bits, see alignment E=4.2e-23 PF03466: LysR_substrate" amino acids 98 to 291 (194 residues), 48.5 bits, see alignment E=7.4e-17

Best Hits

Swiss-Prot: 40% identical to ARGP_PSEAB: HTH-type transcriptional regulator ArgP (argP) from Pseudomonas aeruginosa (strain UCBPP-PA14)

KEGG orthology group: K05596, LysR family transcriptional regulator, chromosome initiation inhibitor (inferred from 91% identity to vei:Veis_5010)

Predicted SEED Role

"Transcriptional regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165JFW7 at UniProt or InterPro

Protein Sequence (303 amino acids)

>Ac3H11_4846 Transcriptional regulator (Acidovorax sp. GW101-3H11)
MSTYDPAALECLAAIVEEGGFERAAQRLNVTQSAVSQRLRALEAQVGSVLIVRSRPLRPT
SAGQLLLKHTKQMRLLRADLERDLQELAPSAPGGTREDERISIAINADSIATWAMGALHD
LVRERLPLEIIVDDQDFTQEWLRSGQVLGCVTTLKQALRGCKMVPLGAMHYVAVASASYA
EQHLPHGLTPHNFRDVSFLSFNRKDDMAAEFVARAFGLKRVALNHLFVPGSEAQMRAVAA
GWAVGVVPELLARGPIADGSMVDLAPGRSLPIQLYWHCWNLESELLDALSAALTGAAAQS
LVS