Protein Info for Ac3H11_4568 in Acidovorax sp. GW101-3H11

Annotation: Heavy metal RND efflux outer membrane protein, CzcC family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 315 PF02321: OEP" amino acids 3 to 112 (110 residues), 28.4 bits, see alignment E=6.9e-11 amino acids 138 to 312 (175 residues), 60.1 bits, see alignment E=1.3e-20

Best Hits

Predicted SEED Role

"Heavy metal RND efflux outer membrane protein, CzcC family" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (315 amino acids)

>Ac3H11_4568 Heavy metal RND efflux outer membrane protein, CzcC family (Acidovorax sp. GW101-3H11)
LPGQRNARGAAVDADVELSQAAVQAGRLHFAGLMREAAWGIAAQKAESDLADAQVRSLQE
ISNDVRRRVKAGDLAHADALAAQSEALAAQSAQLAARQRLSASQSQWMTLTGIALAPDLT
SVPVSEGTAVSPGGAHFAVETHPDARVAALTVERARKRLDVVAATRRDPPELLLRIRQDT
PGRGESAQNSIGVGVRIPLGTASRNQPLQAAALSELDVALTTKQRTEERLAADAAMAWAA
VHTAEQQLEAERQRSALLRERATLIDRSFKAGETPLPELLRALAAATQADTSFARQQVAL
GLARARLQQSLGILP