Protein Info for Ac3H11_4422 in Acidovorax sp. GW101-3H11

Annotation: ATP-dependent helicase DinG/Rad3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 724 PF00270: DEAD" amino acids 63 to 107 (45 residues), 24.6 bits, see alignment 2.9e-09 PF06733: DEAD_2" amino acids 225 to 284 (60 residues), 27.4 bits, see alignment 3.8e-10 PF13307: Helicase_C_2" amino acids 556 to 715 (160 residues), 135.3 bits, see alignment E=3.4e-43

Best Hits

KEGG orthology group: K03722, ATP-dependent DNA helicase DinG [EC: 3.6.4.12] (inferred from 78% identity to aaa:Acav_0023)

Predicted SEED Role

"ATP-dependent helicase DinG/Rad3" in subsystem DNA repair, bacterial DinG and relatives

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.12

Use Curated BLAST to search for 3.6.4.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165JFL7 at UniProt or InterPro

Protein Sequence (724 amino acids)

>Ac3H11_4422 ATP-dependent helicase DinG/Rad3 (Acidovorax sp. GW101-3H11)
MSQQVWAAQALESFDAVVQATEGFRSRAGQRLMAEQVARTFSSATLGKVDEESGEAAPTR
SIAVIQAGTGVGKSLAYCAPAIALALSRGTRVLISTATVALQEQLVNKDLPALAALLPQP
FKFALAKGRGRYVCKLKLDRLAGTGEAEEEADDDLFAEEEAAARAKRPRHETEARMQFYS
TMAQTLSKGAWDGDRDSLDTPPEPEVWSPVAAEGASCTGKHCPAFSQCTYYDKRKELVGA
QVIVANHDLLLSSLGARVLPELDNCLLILDEAHHLPATALQQFACSMDLSRITWIERLSS
RGLRIGALLEVEEIADIPRHAAQLRQTLQDLARIVMDVYGAALKSQKDTWGPARVRVPRG
ELPEQLVAPLGLLAASADGFLEALRAISKALRAEMRDKPEEAKRLSTLYAQIGMLAPRLE
ELHATAQLLLQDAPQGADRSFVPAAKWFTLEVDGDFIVVKAHASPILPGTTLRNHLWSAV
RGAVLTSATLTSCGNFEFFLREAGLHGDEAATSLEVASPFNYAAQGTLIAAETHADPKNA
AQFTAEMVDALLHDIARVEYGALVLFTSREQMRQAVDALPTAMRSVVLVQNALPRTQLLK
RHRERVDNGEPSVIFGMQSFGEGLDLPGRLCESVFITKLPFAPPDDPVGEARAEWLRAVG
RDPFSELVVPATAIRLAQWVGRAIRTEEDQAHVYCYDKRLTRTSYGQRLLKGLPPFALEQ
RAPL