Protein Info for Ac3H11_4391 in Acidovorax sp. GW101-3H11

Annotation: Transcriptional activator of acetoin/glycerol metabolism

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 648 PF01590: GAF" amino acids 76 to 207 (132 residues), 39.9 bits, see alignment E=1.5e-13 PF00158: Sigma54_activat" amino acids 337 to 498 (162 residues), 215.7 bits, see alignment E=8.8e-68 PF14532: Sigma54_activ_2" amino acids 348 to 503 (156 residues), 62.4 bits, see alignment E=1.4e-20 PF02954: HTH_8" amino acids 607 to 642 (36 residues), 49.5 bits, see alignment 7e-17

Best Hits

KEGG orthology group: None (inferred from 65% identity to pol:Bpro_4569)

Predicted SEED Role

"Transcriptional activator of acetoin/glycerol metabolism"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165K522 at UniProt or InterPro

Protein Sequence (648 amino acids)

>Ac3H11_4391 Transcriptional activator of acetoin/glycerol metabolism (Acidovorax sp. GW101-3H11)
VRPNTSPVALRQARQHLLDSGQCPSGLVDERLARSWSRSLAAGLVPTGRPQGIDHPSSGT
LRQVLASNPELLAHSRPVMEYLFEQVRHSQSVVVLADRRGMLMHTLGDPVFVDKAERVAL
TSGASWHEAHRGTNAIGTALAEGCAVEVHGGEHYLERNGFLTCAASPILSATGDLLGILD
ISGDYRNGHAHALGLVSTAARMIENRLLAATCKRNIRLHLHSAPEGIGSVAEGIVAVSGD
GWIVGANRMALAQLGLRAGDVGATLLERVLQVRLDDLLSHHKRRPQQPQAVRVLGGALLF
AQVQMDAAAWVTAPARASAAAAPVVDALAQLDTGDTRWRAAADKARRVVGKPIAVLVQGE
SGVGKEVFARALHASGPRRDAPFVAINCAAIPEHLIESELFGHVAGAFTGARKEGHLGRL
REAQGGTLFLDEIGDMPLALQTRLLRVLQERSVTPVGASKAVPVDFALVCATHQQLLQAA
ELGRFRQDLYYRINGLTVQLPALRERSDFVALAQRLLADLAAEQGLGFEVQVAPDLLARL
AAYPWPGNLRQLANVLRTACAMLAEGEDTLGWEHMPDDLVQALTAAPTPTPAHSEATAPP
TALNLQQLSQAAIDQALQAARGNMSQAARQLGISRQTLYRKLGGRATP