Protein Info for Ac3H11_4376 in Acidovorax sp. GW101-3H11

Annotation: Cellulose synthase catalytic subunit [UDP-forming] (EC 2.4.1.12)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 731 transmembrane" amino acids 41 to 58 (18 residues), see Phobius details amino acids 64 to 81 (18 residues), see Phobius details amino acids 88 to 107 (20 residues), see Phobius details amino acids 122 to 143 (22 residues), see Phobius details amino acids 414 to 434 (21 residues), see Phobius details amino acids 436 to 462 (27 residues), see Phobius details amino acids 488 to 498 (11 residues), see Phobius details amino acids 529 to 549 (21 residues), see Phobius details amino acids 559 to 581 (23 residues), see Phobius details TIGR03030: cellulose synthase catalytic subunit (UDP-forming)" amino acids 42 to 721 (680 residues), 926.5 bits, see alignment E=4.5e-283 PF13641: Glyco_tranf_2_3" amino acids 164 to 391 (228 residues), 53.4 bits, see alignment E=1e-17 PF00535: Glycos_transf_2" amino acids 168 to 332 (165 residues), 88.9 bits, see alignment E=1.1e-28 PF13632: Glyco_trans_2_3" amino acids 246 to 453 (208 residues), 63.1 bits, see alignment E=1e-20 PF03552: Cellulose_synt" amino acids 342 to 571 (230 residues), 32.9 bits, see alignment E=8.3e-12 PF07238: PilZ" amino acids 585 to 681 (97 residues), 48.6 bits, see alignment E=2.6e-16

Best Hits

Swiss-Prot: 63% identical to BCSA_PSEFS: Cellulose synthase catalytic subunit [UDP-forming] (bcsA) from Pseudomonas fluorescens (strain SBW25)

KEGG orthology group: K00694, cellulose synthase (UDP-forming) [EC: 2.4.1.12] (inferred from 63% identity to bav:BAV2631)

Predicted SEED Role

"Cellulose synthase catalytic subunit [UDP-forming] (EC 2.4.1.12)" (EC 2.4.1.12)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.12

Use Curated BLAST to search for 2.4.1.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165K4P9 at UniProt or InterPro

Protein Sequence (731 amino acids)

>Ac3H11_4376 Cellulose synthase catalytic subunit [UDP-forming] (EC 2.4.1.12) (Acidovorax sp. GW101-3H11)
MSVDQRPQADEVADADSHSPQAHWRTVVHAITGWAIWQHPTARVVAVVFSALLMGLVISV
PLDLQGQILFSLGSFAAALLLSKTPGRLSTLAMIVLSISASSRYIYWRFTDTIGFTHWMD
AAFGYGLVLAELYAFAVLLIGYFQTAWPLQRRPVPMPADVSTWPSVDVFIPSYNEPLEVV
RQTVFSAMSLDWPKDRLHVYVLDDGRRTEFREFCEELGVGYLIRDNNHHAKAGNINAALK
VTHSEYIAIFDCDHIPTRSFLQVCMGWFFKDTNLVMLQTPHVFFSPDPFERNLDTFHRMP
NEGELFYGIVQDGNDLWNASFFCGSCAIIRRKELLEVGGIAVETVTEDAHTALKLSRLGY
NTAYLEVPQAAGLATESLSGHVGQRIRWARGMAQIARTDNPLFGKGLHFGQRLCYLNAML
HFFYGLPRLVFLTAPLAYLFFGAHVFQASALMITAYALPHLAHASVTNSRIQGRFRHSFW
NEVYESVLAWYIMRPVLVAAINPKLGKFNVTAKGGVIEKAYFDWTIARPYVVLLLINLVG
MAVGVWKLFSSAGDETTTLVINMVWTVYNIILLGASVAVASETRQIRGTPRVAASLPAVI
RFENGRTLVCKTEDFSQHGLGLAVPPDVDIPMGSRLAVSLFRSDEEGVFPAIVTFSGKGR
LGVKFDNLSLHQQAELASLTFARADAWIATWGTGQRDKPLRSLKSVIVIGLRGMGQLTAT
AFKSLKPLKSR