Protein Info for Ac3H11_4244 in Acidovorax sp. GW101-3H11

Annotation: sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 440 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details transmembrane" amino acids 152 to 173 (22 residues), see Phobius details PF00672: HAMP" amino acids 171 to 223 (53 residues), 35.2 bits, see alignment 1.9e-12 PF02518: HATPase_c" amino acids 327 to 434 (108 residues), 73.8 bits, see alignment E=2.3e-24

Best Hits

KEGG orthology group: None (inferred from 52% identity to bge:BC1002_6278)

Predicted SEED Role

"sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165K1B3 at UniProt or InterPro

Protein Sequence (440 amino acids)

>Ac3H11_4244 sensor histidine kinase (Acidovorax sp. GW101-3H11)
MTLRGWPRSLFGRILLVLALGLALAHALTFVLAFTERSMTMRRAMVSYFASDVASSVAML
ERLPATERAQWVDRLARRNYRFALAEPLDAPEDPSQLARLVANAVAATLPADRPVQVIDP
HVPGTELRLQLRLADGTPLAVDMDEPRLQISPWVLGALALQLALLVGLCAWAVRAATRPL
NTLADAADALGADRPTVPLAENGPREVVRAAAAFNRMQQRIQAHMQERMQILAAVSHDLQ
TPITRLRLRADLLDDPVLQGKLHADLAEMQSLVEEGIAYARSSQAVREPPQRVDLRALVE
SIARDYADAGLPVHLLQAVDVTCDTRPQALRRLVCNLVDNALKFAGAAELTLEAGAPGQW
LVRVLDHGPGIPPAALSAVLQPYVRLEDSRNRGTGGTGLGLAIANELAQALGGRLVLGPR
ADGAQGLEARVELPGTPLLQ