Protein Info for Ac3H11_3726 in Acidovorax sp. GW101-3H11
Annotation: Hydroxymethylpyrimidine ABC transporter, substrate-binding component
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02051, sulfonate/nitrate/taurine transport system substrate-binding protein (inferred from 82% identity to vpe:Varpa_5415)Predicted SEED Role
"Hydroxymethylpyrimidine ABC transporter, substrate-binding component" in subsystem Thiamin biosynthesis
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A165IQB1 at UniProt or InterPro
Protein Sequence (332 amino acids)
>Ac3H11_3726 Hydroxymethylpyrimidine ABC transporter, substrate-binding component (Acidovorax sp. GW101-3H11) MMKTASRLSKLGAAALLALGAVGTMQAHAQEKFTYMTNWYAQAEHGGFYQAVATGLYKKY GLDVTIKMGGPQVNIVQMMAAGQAECVMGSSDLQMIQMREGGVPVVNVAAVFQKDPQVLI AHDDVKKFEDLKGKTILIASSAQRGYWPWLKAKYGFTDSQTRPYTFNIQPFVADKNTAQQ GYLTSEPFAIAKAGVKANTLMFSDQGYPAYATTISCMEKTVKDRSAAVASFVKASMEGWK SYLADPAPANALIKKDNPNMTDEQLAYSVAKLKEMGMATGGDATTMGIGIMTDARAKASY DFLVDAKLIDPAKVKLAETYNTAFVKDLKVLP