Protein Info for Ac3H11_3592 in Acidovorax sp. GW101-3H11
Annotation: Carbon monoxide dehydrogenase medium chain (EC 1.2.99.2)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 37% identical to DCMM_HYDPS: Carbon monoxide dehydrogenase medium chain (cutM) from Hydrogenophaga pseudoflava
KEGG orthology group: K03519, carbon-monoxide dehydrogenase medium subunit [EC: 1.2.99.2] (inferred from 82% identity to vei:Veis_4542)Predicted SEED Role
"Carbon monoxide dehydrogenase medium chain (EC 1.2.99.2)" in subsystem CO Dehydrogenase (EC 1.2.99.2)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.2.99.2
Use Curated BLAST to search for 1.2.99.2
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A165J2Q9 at UniProt or InterPro
Protein Sequence (263 amino acids)
>Ac3H11_3592 Carbon monoxide dehydrogenase medium chain (EC 1.2.99.2) (Acidovorax sp. GW101-3H11) MYAFTFEAPTSVAAAAQHIAQGGKLLAGGQSLLPSMRLRLANPEKIVDLNGVAELAGIRR DGNALVIGAMTRHMDVASSADVKAAIPALADLAAHIGDRQVRARGTLGGSVANNDPAACY PSAVLGLGATVITNKREIAADDFFVGMYTTALEEGEIITAIRFPIPQRAAYMKFKQPASR FSLVGVFVAQTDSGVRVAITGAATSVFRHAGLEAALSQSFTAAAAAGVTIDASDLNSDIH ASAAYRANLISVQTQRAVQKMLG