Protein Info for Ac3H11_3035 in Acidovorax sp. GW101-3H11

Updated annotation (from data): Fructose ABC transporter, substrate-binding component FrcB
Rationale: Specific phenotype: utilization of D-Fructose, D-Mannose, D-Sorbitol
Original annotation: Fructose ABC transporter, substrate-binding component FrcB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 337 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF00532: Peripla_BP_1" amino acids 30 to 256 (227 residues), 79.7 bits, see alignment E=2.7e-26 PF13407: Peripla_BP_4" amino acids 32 to 301 (270 residues), 161.2 bits, see alignment E=3.6e-51

Best Hits

KEGG orthology group: K10552, fructose transport system substrate-binding protein (inferred from 83% identity to vei:Veis_0540)

Predicted SEED Role

"Fructose ABC transporter, substrate-binding component FrcB" in subsystem Fructose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165JQ36 at UniProt or InterPro

Protein Sequence (337 amino acids)

>Ac3H11_3035 Fructose ABC transporter, substrate-binding component FrcB (Acidovorax sp. GW101-3H11)
MQRTPAFALSALALTGALACGLAQAQTSEPVIGLITKTETNPFFVKMKEGATAEAKKLGA
KLVSAAGKTDGDNAGQVTAMENLIAAGAKTILITPSDAKAIVPAIKKAQAKGVMVIALDS
PTEPMDATDALFATDNYKAGELIGQYAKAAAAGKKPVIATLDLFPGHPVGAQRHNGFLKG
FGLQANDAKSNELSRPAEVVCMADSFGDRAKGQTGMENCLQKNPDINIVYTINEPAAAGA
YNALKAAGKEKNVLIVSVDGGCAGIADVGKGVIAATSQQYPLRMAAMGVAAGVEYAKTGK
KVSGYTDTGVTLIAAKPMAGVDSKDVKTGTDLCWGAK