Protein Info for Ac3H11_2955 in Acidovorax sp. GW101-3H11

Annotation: Cytosine/purine/uracil/thiamine/allantoin permease family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 485 transmembrane" amino acids 43 to 62 (20 residues), see Phobius details amino acids 72 to 92 (21 residues), see Phobius details amino acids 120 to 148 (29 residues), see Phobius details amino acids 161 to 181 (21 residues), see Phobius details amino acids 193 to 212 (20 residues), see Phobius details amino acids 233 to 250 (18 residues), see Phobius details amino acids 271 to 293 (23 residues), see Phobius details amino acids 307 to 330 (24 residues), see Phobius details amino acids 349 to 369 (21 residues), see Phobius details amino acids 376 to 401 (26 residues), see Phobius details amino acids 422 to 446 (25 residues), see Phobius details amino acids 458 to 480 (23 residues), see Phobius details TIGR00800: NCS1 nucleoside transporter family" amino acids 25 to 444 (420 residues), 353.2 bits, see alignment E=9.8e-110 PF02133: Transp_cyt_pur" amino acids 31 to 468 (438 residues), 377.9 bits, see alignment E=3.5e-117

Best Hits

KEGG orthology group: K03457, nucleobase:cation symporter-1, NCS1 family (inferred from 87% identity to aav:Aave_0968)

Predicted SEED Role

"Cytosine/purine/uracil/thiamine/allantoin permease family protein" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165L3E7 at UniProt or InterPro

Protein Sequence (485 amino acids)

>Ac3H11_2955 Cytosine/purine/uracil/thiamine/allantoin permease family protein (Acidovorax sp. GW101-3H11)
MTNSTGSAAHVAGLMPGGASNTLANEDLLPTTAAQRHWTWKDFAALWVGMVVCVPTYTMA
SSMLDQGFTWQMAVWLVFLANCIVLVPMVLIGRVGPKYGVPFPVLARASFGVKGANLPAV
LRGLVACGWFSINCYFGALALHGFLNILGMGLAGPAEGQTISTSQFMCFLAFWAVHIYFI
WKGPESIRKLEVIAAPLMIIASIVLVVVLMMKVPSGQLFNLPAKVVEGGPKTWAALTGLV
GFWATLALNIPDFTRFAKTQKDQVMGQAIGLPIPMALFSMVGVIGFSASAILYGKAQLFP
DGLLTQMGSVAAGVGLLVILLANLTTNVAANLVSPSYDFSQVAPSKISFRMGGLIAALIG
LVFMPWKLLATSGGYLFTWLGGYGTLLGAIAGILLVDYYLVRKSELKVDDLYRRGGEYEY
SNGWNVQALIAFALGVLPCLPGYLAVSGVIDKAAVPGLLLALFDFGWFFSLAVAGTYYYL
TAKKK