Protein Info for Ac3H11_2819 in Acidovorax sp. GW101-3H11

Annotation: IncF plasmid conjugative transfer pilus assembly protein TraH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 482 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF06122: TraH" amino acids 37 to 395 (359 residues), 334.1 bits, see alignment E=6.6e-104

Best Hits

KEGG orthology group: K12072, conjugative transfer pilus assembly protein TraH (inferred from 100% identity to adk:Alide2_2818)

Predicted SEED Role

"IncF plasmid conjugative transfer pilus assembly protein TraH" in subsystem Type 4 secretion and conjugative transfer

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165L0Z2 at UniProt or InterPro

Protein Sequence (482 amino acids)

>Ac3H11_2819 IncF plasmid conjugative transfer pilus assembly protein TraH (Acidovorax sp. GW101-3H11)
MSRPSRPVRARKAVALAAALVVLSATLPARADLNSEVNDMFNNLGAIGNYTAPGAFRGQT
YNTYTGGSLMMRSPNKVYQLAAIQFPSVKAGCGGIDVFGGSFSHISAQEFKNLLRNITAA
LPGIAFQLALEAVSPLLGGLTKWAKGLETWINNARINSCETAKAIVSSAAEAVGYSSQET
CSDLAMEMGLESDRDAARRRCWTDRPSILSSARSSGDANVRNKAPFVGNLTWKALQYTGS
SLDDAGRELIMSMVGTVIYYPEESGRDPEPIAPTLTSISQLLYGQAAGSGNNVIQHLLRC
NDYSTCDVVSTNTAYDHVPFTARVETMMRSIADRIATRTAIPNNSAEVGFVNQTTEPVYK
MLSVGTSIPGSGLADSLIGQYRDVIAADYAHVFLERNLRLGMAALAKDYTLQQTQRDQAN
QIRQRAQAILLQISQEKNLLYAKVGSYRAVASHLEQLERQLRSSMPQHVMDMLGQQAAHL
SR