Protein Info for Ac3H11_266 in Acidovorax sp. GW101-3H11

Annotation: DNA internalization-related competence protein ComEC/Rec2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 856 transmembrane" amino acids 32 to 46 (15 residues), see Phobius details amino acids 56 to 76 (21 residues), see Phobius details amino acids 92 to 113 (22 residues), see Phobius details amino acids 317 to 338 (22 residues), see Phobius details amino acids 349 to 372 (24 residues), see Phobius details amino acids 378 to 394 (17 residues), see Phobius details amino acids 402 to 420 (19 residues), see Phobius details amino acids 423 to 442 (20 residues), see Phobius details amino acids 462 to 489 (28 residues), see Phobius details amino acids 493 to 520 (28 residues), see Phobius details amino acids 534 to 558 (25 residues), see Phobius details amino acids 565 to 581 (17 residues), see Phobius details PF13567: DUF4131" amino acids 58 to 241 (184 residues), 86.3 bits, see alignment E=3e-28 TIGR00361: DNA internalization-related competence protein ComEC/Rec2" amino acids 197 to 822 (626 residues), 335 bits, see alignment E=7.7e-104 PF03772: Competence" amino acids 295 to 561 (267 residues), 198.2 bits, see alignment E=2.6e-62 TIGR00360: ComEC/Rec2-related protein" amino acids 316 to 500 (185 residues), 89.7 bits, see alignment E=2.7e-29 PF00753: Lactamase_B" amino acids 596 to 793 (198 residues), 47 bits, see alignment E=4.6e-16

Best Hits

KEGG orthology group: K02238, competence protein ComEC (inferred from 72% identity to vei:Veis_0403)

Predicted SEED Role

"DNA internalization-related competence protein ComEC/Rec2"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165JMA1 at UniProt or InterPro

Protein Sequence (856 amino acids)

>Ac3H11_266 DNA internalization-related competence protein ComEC/Rec2 (Acidovorax sp. GW101-3H11)
MPAISASNATTLPRPEGALGAGDWLQPVAPWQLPALLLGVVAGAALQLQQPGLWDAGAYA
ALLCAALVVGWCGVAASRPCRPGAVRHARGRAAAAAVLVLLAGAMAMAAVSGLRATAYLQ
QGLNPALEGQDIRVTGVVSAMPQTNEAGTRLRLEVVSALLQGSPVQLPPRIEVAWYGGAF
VRDAGDAVDLQRQPAPVRAGERWEMTVRLKAPHGLRNPHGFDFELWAWEQGVQATGYVRA
GPKDVPPRRQATTWQHPVEQARQSVRDALLDRLGRGADEASDPGRARIAGVVAALVTGDQ
RAIDRADWDMFRATGVAHLMSISGLHITLFAWLAAAVVRTLWRRSMRLCLWVPAPSAALL
AGVVLASAYALFSGWGVPAQRTVIMLCTVALLQWSGRRWPWPHVWLLACAAVVLADPWAL
AQAGFWLSFVAVGVLFATNPIAGKVYGTGVKGHFYALFREQWVVTLALTPLSLLLFGQVS
VVGFVANLVAIPWVTLVVTPLALGGVVWAPLWSLAAWSLWPLTAWLQWLAQWPGAVLFLP
AAPLWAGVAAVAGGALLAMRLPWRLRLLALPLLLPVLWWQPARPAAGQFELLAADIGQGN
AVLVRTATHSLLYDAGPRFSRESDAGHRVLVPLLRALGERVDVLMLSHRDADHTGGAAAV
LAQQPGAELTGSIEADHGLQALRPARPCLAGQRWEWDGVAFEVLHPLAGDGAPATRPPRP
NTLSCVLRVVAAGAQAPSVLLVGDIEAAQEQALVARGAALQADLLLVPHHGSKTSSSPAL
LEAVQPRTALVQAGYRNRFGHPAPDVLQRYRERDIRVVESSRCGAATWVSVAPDAVACER
DTGRRYWQHSMVPRSD